# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2034648 | F | Activation of RXFP1 expressed in HEK-293T cells assessed as induction of cAMP accumulation after 6 hrs by beta galactosidase reporter gene assay | 3 | cell-based format | Scientific Literature | |||
2. | ALA2034746 | B | Displacement of europium-labelled H2 relaxin from RXFP1 expressed in HEK-293T cells | 3 | cell-based format | Scientific Literature | |||
3. | ALA1613930 | F | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) | Homo sapiens | 4,937 | assay format | PubChem BioAssays | ||
4. | ALA1737977 | F | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1: THP1 Hit Validation. (Class of assay: confirmatory) | 385 | assay format | PubChem BioAssays | |||
5. | ALA1738202 | F | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1: RXFP1 Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2676, AID2703, AID489043, AID492948] | Homo sapiens | 344 | assay format | PubChem BioAssays | ||
6. | ALA3720763 | F | Agonist activity at human RXFP1 receptor expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
7. | ALA3720764 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay | Homo sapiens | 167 | cell-based format | Patent Bioactivity Data | ||
8. | ALA3720765 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay relative to forskolin | Homo sapiens | 167 | cell-based format | Patent Bioactivity Data | ||
9. | ALA3720767 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as increase cell impedance at 250 to 750 nM measured every 10 to 30 secs for 1 hr by real time cell analyzer method | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
10. | ALA3720768 | F | Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay | Homo sapiens | 8 | cell-based format | Patent Bioactivity Data | ||
11. | ALA3720839 | F | Agonist activity at human RXFP1 receptor M11 Asp659Gly and Ser660Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
12. | ALA3720840 | F | Agonist activity at human RXFP1 receptor expressed in HEK293 cells assessed as stimulation of cAMP production at 66 uM incubated for 30 mins by TR-FRET based HTRF assay relative to relaxin | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA3720842 | F | Agonist activity at chimeric mouse-human RXFP1 receptor expressed in HEK293 cells assessed as stimulation of cAMP production at 66 uM incubated for 30 mins by TR-FRET based HTRF assay relative to relaxin | 1 | cell-based format | Patent Bioactivity Data | |||
14. | ALA3720844 | F | Agonist activity at human RXFP1 receptor M11 Asp659Gly and Ser660Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production at 66 uM incubated for 30 mins by TR-FRET based HTRF assay relative to relaxin | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
15. | ALA3720846 | F | Agonist activity at mouse RXFP1 receptor with humanized extracellular loop 3 (M10/M11) expressed in HEK293 cells assessed as stimulation of cAMP production at 66 uM incubated for 30 mins by TR-FRET based HTRF assay relative to relaxin | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
16. | ALA4156525 | F | Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
17. | ALA4156526 | F | Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay relative to forskloin | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
18. | ALA4323798 | F | Antagonist activity at human RXFP1 assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed by mutRelaxin agonist addition measured after 60 mins by cell based TR-FRET assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4432204 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK-293T cells cotransfected with beta-galactosidase assessed as cAMP activation by beta-galactosidase reporter gene assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
20. | ALA4432205 | F | Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK-293T cells cotransfected with beta-galactosidase assessed as cAMP activation at 10 uM by beta-galactosidase reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature |