| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1614398 | F | PUBCHEM_BIOASSAY: Confirmatory Assay for General miRNAs Modulators and/or Inhibitors/Activators of miR-21. (Class of assay: confirmatory) [Related pubchem assays: 2288, 2289 ] | Homo sapiens | 106 | ALA1201862 | assay format | PubChem BioAssays | |
| 2. | ALA1614146 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Inhibitors of miR-21. (Class of assay: confirmatory) | Homo sapiens | 31,975 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1613836 | F | PUBCHEM_BIOASSAY: qHTS Assay for Modulators of miRNAs and/or Activators of miR-21. (Class of assay: confirmatory) | Homo sapiens | 31,975 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1737960 | F | PUBCHEM_BIOASSAY: Confirmatory Assay for General miRNAs Modulators and/or Inhibitors/Activators of miR-21: second round cherrypicks. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2507, AID2508, AID2598] | Homo sapiens | 54 | ALA1201862 | assay format | PubChem BioAssays | |
| 5. | ALA4256889 | B | Inhibition of miR-21 RNA in human HeLa cells harboring miR-21 binding sequence in 3'-UTR of firefly luciferase gene assessed as increase in luciferase expression incubated for 48 hrs by Bright-Glo luciferase reporter gene assay relative to control | Homo sapiens | 37 | ALA4251758 | cell-based format | Scientific Literature | |
| 6. | ALA4256890 | B | Inhibition of miR-21 RNA in human HeLa cells harboring miR-21 binding sequence in 3'-UTR of firefly luciferase gene assessed as increase in luciferase expression incubated for 48 hrs by Bright-Glo luciferase reporter gene assay | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 7. | ALA4256901 | B | Inhibition of promoter activity of miR-21 RNA (unknown origin) transfected in human HeLa cells at 10 uM after 48 hrs by Bright-Glo luciferase reporter gene assay | Not specified | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 8. | ALA4256910 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced cytotoxicity after 72 hrs by XTT assay | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 9. | ALA4256911 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced cytotoxicity by measuring reduction in topotecan IC50 at 10 uM after 72 hrs by XTT assay relative to topotecan alone | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 10. | ALA4256912 | B | Inhibition of miR-21 RNA (unknown origin) transfected in human HeLa cells at 0.1 to 1000 nM after 48 hrs by Bright-Glo luciferase reporter gene assay | Not specified | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 11. | ALA4256915 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced inhibition of colony formation by measuring topotecan IC50 at at 10 uM after 2 weeks by crystal violet staining-based microscopic analysis (Rvb = 2 uM) | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 12. | ALA4256917 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced apoptosis by measuring increase in caspase-3/7 activity at 10 uM after 24 hrs by Caspase-Glo 3/7 assay relative to control | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 13. | ALA4256918 | B | Inhibition of miR-21 RNA in human A498 cells assessed as increase in PDCD4 expression at 10 uM after 48 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 14. | ALA4256919 | B | Inhibition of miR-21 RNA in human A498 cells assessed as increase in PTEN expression at 10 uM after 48 hrs by Western blot analysis relative to control | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 15. | ALA4256920 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced cytotoxicity by measuring topotecan IC50 at 10 uM after 72 hrs by XTT assay (Rvb = 1 uM) | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 16. | ALA4256922 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced inhibition of colony formation by measuring reduction in topotecan IC50 at at 10 uM after 2 weeks by crystal violet staining-based microscopic analysis relative to topotecan alone | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 17. | ALA4256924 | B | Inhibition of miR-21 RNA in human A498 cells assessed as potentiation of topotecan-induced apoptosis by measuring increase in caspase-3/7 activity at 10 uM after 24 hrs by Caspase-Glo 3/7 assay relative to topotecan alone | Homo sapiens | 1 | ALA4251758 | cell-based format | Scientific Literature | |
| 18. | ALA4364424 | B | Binding affinity to biotinylated pre-miRNA-21 (unknown origin) by SPR analysis | Not specified | 7 | ALA4364240 | nucleic acid format | Scientific Literature | |
| 19. | ALA4364426 | B | Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation preincubated for 15 mins followed by pre-miRNA-21 addition and measured after 5 hrs by cat-ELCCA | Not specified | 14 | ALA4364240 | nucleic acid format | Scientific Literature | |
| 20. | ALA4364428 | B | Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation at 1 mM measured after 15 mins by cat-ELCCA relative to control | Not specified | 15 | ALA4364240 | nucleic acid format | Scientific Literature |
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