| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1686896 | F | Agonist activity at 5-oxo-ETE receptor in human neutrophils assessed as stimulation of ca2+ mobilization at 100 nM in presence of 5-oxo-ETE | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA1686897 | F | Agonist activity at 5-oxo-ETE receptor in human neutrophils assessed as stimulation of ca2+ mobilization | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA1764243 | F | Agonist activity at 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as stimulation intracellular calcium level at 10 nM followed by vehicle addition in presence of digitonin added at 3.5 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1764244 | F | Agonist activity at 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as stimulation intracellular calcium level at 100 nM followed by 5-oxo-ETE addition at 2.5 mins in presence of digitonin added at 3.5 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1764428 | F | Desensitization of 5-oxo-ETE receptor in indo-1-labeled human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 6. | ALA2339755 | F | Antagonist activity at OXE receptor in human neutrophils assessed as 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addition measured at 1 uM after 1 min by spectrofluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA2339756 | F | Antagonist activity at OXE receptor in human neutrophils assessed as LTB4-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addition measured after 1 min by spectrofluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2339757 | F | Antagonist activity at OXE receptor in human neutrophils assessed as 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addition measured at 30 uM after 1 min by spectrofluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2339758 | F | Antagonist activity at OXE receptor in human neutrophils assessed as induction of Ca2+ mobilization at 30 uM after 2 mins by spectrofluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2339759 | F | Antagonist activity at OXE receptor in human neutrophils assessed as 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addition measured after 1 min by spectrofluorimetric analysis | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 11. | ALA2339760 | F | Agonist activity at OXE receptor in human neutrophils assessed as 5-oxo-ETE-induced Ca2+ mobilization incubated for 2 mins prior to 5-oxo-ETE addition measured after 1 min by spectrofluorimetric analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 12. | ALA3117757 | F | Antagonist activity at human OXE receptor fused with G-alphai assessed as inhibition of 5-oxo-ETE-induced GTPgammaS binding after 60 mins by liquid scintillation counting analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 13. | ALA3117762 | B | Antagonist activity at OXE receptor (unknown origin) expressed in neutrophils assessed as inhibition of 5-oxo-ETE-induced cell migration after 2 hrs by hematoxylin/chromotrope 2R staining-based microscopic analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA3117763 | B | Potency index, ratio of compound activity to Gue1654 activity for antagonism of OXE receptor (unknown origin) expressed in anti-CD49d-labeled neutrophils assessed as inhibition of 5-oxo-ETE-induced F-actin polymerization | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA3117764 | B | Potency index, ratio of compound activity to Gue1654 activity for antagonism of OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin polymerization | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA3117765 | B | Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled neutrophils assessed as inhibition of 5-oxo-ETE-induced F-actin polymerization preincubated for 5 mins followed by 5-oxo-ETE induction measured after 20 secs by flow cytometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 17. | ALA3117953 | B | Antagonist activity at OXE receptor (unknown origin) expressed in anti-CD49d-labeled eosinophils assessed as inhibition of 5-oxo-ETE-induced F-actin polymerization preincubated for 5 mins followed by 5-oxo-ETE induction measured after 20 secs by flow cytometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 18. | ALA3118914 | F | Antagonist activity at OXE receptor in human neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization by spectrofluorometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 19. | ALA3118915 | F | Antagonist activity at OXE receptor (unknown origin) expressed in indo-1 loaded neutrophils assessed as inhibition of 5-oxo-ETE-induced calcium mobilization incubated for 2 mins prior to 5-oxo-ETE induction by spectrofluorometric analysis | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 20. | ALA3225356 | F | Agonist activity at OXE receptor (unknown origin) expressed in HEK293 cells co-expressing Galpha subunit G16 assessed as calcium mobilization using Oregon Green 488 BAPTA-1/AM by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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