| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2390160 | B | Inhibition of human TRPV6 transfected in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2390162 | B | Ratio of 2-APB IC50 to compound IC50 for human TRPV6 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2390165 | B | Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx up to 500 uM after 5 mins by FLIPR assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA2390166 | B | Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx up to 500 uM after 5 mins by FLIPR assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA2388391 | B | Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 6. | ALA2388392 | B | Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 7. | ALA4220008 | B | Inhibition of TRPV6 (unknown origin) expressed in HEK293 cells by whole cell patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4308162 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx at 10 uM preincubated for 5 mins followed by CdCl2 addition measured under dark state by calcium-5 fluorescence dye-based FLIPR assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4308166 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition measured under dark state by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4308168 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx at 10 uM preincubated for 5 mins followed by CdCl2 addition using 365 nm UV-light irradiated compound by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4308169 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx preincubated for 5 mins followed by CdCl2 addition using 365 nm UV-light irradiated compound by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4308170 | B | Inhibition of human peTFP-C1-TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential by patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4308175 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction of Cd2+ influx preincubated for 5 mins followed by CdCl2 addition by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4308177 | B | Inhibition of human YFP-fused TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential under 365 nm UV-light irradiation by patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4308178 | B | Inhibition of human YFP-fused TRPV6 expressed in HEK293 cells assessed as decrease in whole cell inward calcium current density at 10 uM at 50 mV holding potential pre-irradiated with 365 nm UV-light followed by 470 nm UV-light irradiation by patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4388814 | B | Agonist activity at human TRPV6 expressed in human HEK293 cells assessed as increase in Ca2+ transport at 50 uM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4388815 | B | Agonist activity at human TRPV6 expressed in human HEK293 cells assessed as increase in Ca2+ transport at 100 nM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4388817 | B | Antagonist activity at human TRPV6 expressed in human HEK293 cells assessed as reduction in Ca2+ transport at 2.5 uM incubated for 5 mins by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4680527 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 20. | ALA4680528 | B | Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx up to 100 uM by calcium-5 fluorescence dye-based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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