# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3361962 | B | Blocking of human TRPM5 expressed in HEK293 cells by FLIPR membrane potential/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA3361963 | B | Induction of human TRPM5 opening expressed in HEK293 cells by FLIPR membrane potential/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3880020 | B | Inhibition of human TRPM5 transfected in HEK293 cells assessed as inhibition of ATP-mediated calcium mobilization by Calcium3 dye-based FLIPR assay | Homo sapiens | 68 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3880021 | B | Inhibition of human TRPM5 transfected in HEK293 cells assessed as inhibition of KCl-stimulated membrane potential by FLIPR assay | Homo sapiens | 68 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4015190 | B | Inhibition of human TRPM5 expressed in HEK293 cells assessed as decrease in carbachol-evoked membrane depolarization at 22 uM preincubated for 2 mins followed by carbachol addition measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4015204 | B | Agonist activity at human TRPM5 expressed in HEK293 cells assessed as induction of membrane depolarization at 33 uM measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA4824105 | B | Agonist activity at human TRPM5 expressed in CHO-K1 cells maintained at 80 mV final holding potential by syncroPatch assay | Homo sapiens | 72 | cell-based format | Scientific Literature | ||
8. | ALA4824106 | B | Agonist activity at human TRPM5 expressed in CHO-K1 cells maintained at 80 mV final holding potential by QPatch HTX assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5153224 | B | Agonist activity at TRPM5 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA5153226 | B | Antagonist activity at TRPM5 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA5153227 | B | Agonist activity at human TRPM5 expressed in HEK cells by whole cell electrophysiology method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5153228 | B | Agonist activity at human TRPM5 in HEK293T cells by FLIPR based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5153235 | B | Agonist activity at human TRPM5 expressed in CHO-K1 cells assessed as increase in relative fluorescence unit measured for 2 mins by FLIPR based membrane potential assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
14. | ALA5153271 | B | Agonist activity at human TRPM5 expressed in human Caco-2 cells assessed as increase in acetylcholine release at 50 uM incubated for 18 hrs by mass spectrometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5153272 | B | Agonist activity at human TRPM5 expressed in human Caco-2 cells assessed as increase in acetylcholine release at 50 uM incubated for 18 hrs in the presence of N'-(3,4-dimethoxybenzylidene)-2-phenylcyclopropanecarbohydrazide by mass spectrometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5153273 | B | Agonist activity at human TRPM5 expressed in human Caco-2 cells assessed as increase in acetylcholine release at 50 uM incubated for 18 hrs in the presence of N'-(3,4-dimethoxybenzylidene)-2-(naphthalen-1-yl)acetohydrazide by mass spectrometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |