# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1908807 | B | Binding constant for TRPM6 kinase domain | 72 | single protein format | Scientific Literature | |||
2. | ALA1175107 | B | Inhibition of TRPM6 at 10 uM | 2 | single protein format | Scientific Literature | |||
3. | ALA2209248 | B | Inhibition of TRPM6 assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
4. | ALA3734575 | F | Inhibition of TRPM6 (unknown origin) expressed in HEK293 cells assessed as effect on agonist-induced Ca2+ changes | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4025422 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA4044233 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4055268 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
8. | ALA4157312 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA4186091 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4230991 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA4264580 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA4308089 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA4333671 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA4358169 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA4366006 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
16. | ALA4382800 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
17. | ALA4389519 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
18. | ALA4389996 | B | Inhibition of wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
19. | ALA4391622 | B | Binding affinity to wild-type human partial length TRPM6 (Q1723 to I1998 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
20. | ALA4805204 | B | Inhibition of human TRPM6 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control | Homo sapiens | 1 | single protein format | Patent Bioactivity Data |