| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2034649 | F | Agonist activity at RXFP4 expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation after 6 hrs by beta galactosidase reporter gene assay | 3 | cell-based format | Scientific Literature | |||
| 2. | ALA2034744 | B | Displacement of europium-labelled mouse INSL-5 from RXFP4 expressed in CHO-K1 cells | 3 | cell-based format | Scientific Literature | |||
| 3. | ALA3100260 | F | Agonist activity at human RXFP4 transfected in CHO-K1 cells at 0.01 nM to 1000 nM by beta-galactosidase reporter gene assay relative to forskolin | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3100734 | F | Agonist activity at human RXFP4 transfected in CHO-K1 cells up to 10 uM by beta-galactosidase reporter gene assay relative to forskolin | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3100735 | F | Agonist activity at human RXFP4 transfected in CHO-K1 cells at 10 uM by beta-galactosidase reporter gene assay relative to forskolin | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3100736 | F | Agonist activity at human RXFP4 transfected in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP production by beta-galactosidase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA3100737 | B | Displacement of Eu(A)-mINSL5 acid from human RXFP4 transfected in CHO-K1 cells by fluorescence-based assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA3361949 | B | Agonist activity at human GPR100 expressed in U2OS cells by FLIPR/summary (Abse5) assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4402088 | F | Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4402089 | F | Agonist activity at human RXFP4 expressed in CHOK1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP accumulation preincubated for 30 mins followed by forskolin-stimulation and measured after 30 mins by HTRF assay relative to relaxin-3 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4402091 | F | Agonist activity at human RXFP4 expressed in CHOK1 cell membranes assessed as stimulation of [35S]-GTPgammaS binding after 3 hrs by scintillation counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4432202 | B | Displacement of Eu-INSL5 from human RXFP4 receptor expressed in CHOK1 cells by time-resolved fluorescent whole cell binding assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 13. | ALA4432203 | F | Agonist activity at human RXFP4 receptor expressed in CHOK1 cells cotransfected with beta-galactosidase assessed as inhibition of forskolin-stimulated cAMP by beta-galactosidase reporter gene assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 14. | ALA4673074 | B | Competitive binding affinity to human RXFP4 receptor transfected in CHO-K1 cells in presence of europium-labeled Eu(A)-R3/I5 by fluorometric analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4673075 | F | Agonist activity at human RXFP4 transfected in CHO-K1 cells co-transfected with pCRE-beta-galactosidase reporter plasmid assessed as inhibition of forskolin-induced cAMP accumulation measured after 6 hrs by beta-galactosidase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4716965 | B | Displacement of europium-labeled Eu(A)-mINSL5 from human RXFP4 expressed in CHO-K1 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 17. | ALA4716966 | F | Agonist activity at human RXFP4 expressed in CHO-K1 cells assessed as reduction in forskolin-induced cAMP production by pCRE beta-galactosidase reporter assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 18. | ALA4716967 | B | Agonist activity at human RXFP4 expressed in CHO-K1 cells assessed as induction of ERK1/2 phosphorylation incubated for 5 mins by Alpha-screen sure-fire assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4731846 | F | Agonist activity at RXFP4 (unknown origin) stably expressed in CHO cells co-transfected with pCRE assessed as inhibition of forskolin-induced cAMP accumulation measured after 6 hrs by beta-galactosidase reporter gene assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA4883591 | B | PRESTO-Tango GPCRome screening (RXFP4) | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt |
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