# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1640079 | A | Inhibition of rat aldehyde oxidase | Rattus norvegicus | 8 | ALA1629464 | single protein format | Scientific Literature | |
2. | ALA2025441 | A | Metabolic stability in rat cytosol assessed as aldehyde oxidase-mediated pyridine ring oxidation of compound by HPLC and LC/MS analysis | Rattus norvegicus | 1 | ALA2021836 | assay format | Scientific Literature | |
3. | ALA3530541 | A | Activity of aldehyde oxidase in hepatocytes isolated from chimeric mouse transplanted with rat hepatocytes assessed as enzyme-mediated drug metabolism treated with FK3453 at 10 uM after 2 hrs by LC/MS/MS analysis | Rattus norvegicus | 13 | ALA3526077 | cell-based format | Scientific Literature | |
4. | ALA3530542 | A | Activity of aldehyde oxidase in hepatocytes isolated from chimeric mouse transplanted with rat hepatocytes assessed as enzyme-mediated drug metabolism measured as compound remaining at 10 uM after 2 hrs by LC/MS/MS analysis | Rattus norvegicus | 1 | ALA3526077 | cell-based format | Scientific Literature | |
5. | ALA4039261 | A | Drug level in rat hepatic S9 fraction treated with VU0424238 assessed as AO-mediated metabolite formation by LC/MS analysis | Rattus norvegicus | 1 | ALA4038301 | assay format | Scientific Literature | |
6. | ALA4039309 | A | Drug metabolism in rat hepatic S9 fraction assessed as AO-mediated metabolite formation by LC/MS analysis | Rattus norvegicus | 1 | ALA4038301 | assay format | Scientific Literature | |
7. | ALA4322296 | A | Substrate activity at aldehyde oxidase in IGS SD rat liver cytosol assessed as enzyme-mediated metabolism by measuring half life at 1 uM after 30 to 120 mins by LC/MS/MS analysis | Rattus norvegicus | 12 | ALA4321795 | subcellular format | Scientific Literature | |
8. | ALA4322299 | A | Substrate activity at aldehyde oxidase in rat liver cytosol assessed as enzyme-mediated drug uptake by mass spectrophotometric analysis | Rattus norvegicus | 2 | ALA4321795 | subcellular format | Scientific Literature | |
9. | ALA4322302 | A | Substrate activity at aldehyde oxidase in rat liver cytosol assessed as enzyme-mediated drug uptake at 1 uM | Rattus norvegicus | 3 | ALA4321795 | subcellular format | Scientific Literature | |
10. | ALA4322316 | A | Drug level in Sprague-Dawley rat plasma treated with [14C]momelotinib assessed as aldehyde oxidase mediated compound formation at 15 mg/kg, po measured up to 48 hrs by liquid scintillation counting | Rattus norvegicus | 1 | ALA4321795 | organism-based format | Scientific Literature |