| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1648139 | B | Binding affinity to human GRB7 SH2-apo domain expressed in Escherichia coli BL21 (DE3) assessed as change in melting temperature at 100 uM by thermofluor based melting point shift assay | Homo sapiens | 12 | assay format | Scientific Literature | ||
| 2. | ALA1648303 | B | Binding affinity to human GRB7 SH2-apo domain expressed in Escherichia coli BL21 (DE3) assessed as change in melting temperature at 200 uM by thermofluor based melting point shift assay | Homo sapiens | 12 | assay format | Scientific Literature | ||
| 3. | ALA1648304 | B | Binding affinity to human GRB7 expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 4. | ALA1648305 | B | Binding affinity to human GRB7 SH2-apo domain expressed in Escherichia coli BL21 (DE3) assessed as melting temperature at 100 uM by thermofluor based melting point shift assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA1648306 | B | Binding affinity to human GRB7 SH2-NSC642056 domain expressed in Escherichia coli BL21 (DE3) assessed as melting temperature at 100 uM by thermofluor based melting point shift assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA3624249 | B | Binding affinity to GST-tagged Grb7-SH2 domain (415 to 532 amino acid residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using 20 mM Tris buffer by SPR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA3624250 | B | Binding affinity to GST-tagged Grb7-SH2 domain (415 to 532 amino acid residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using 50 mM NaPO4 buffer by SPR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 8. | ALA3624251 | B | Binding affinity to GST-tagged Grb7-SH2 domain (415 to 532 amino acid residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using 350 mM NaPO4 buffer by SPR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA3624252 | B | Binding affinity to GST-tagged Grb7-SH2 domain (415 to 532 amino acid residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using 20 mM Tris/1 mM NaPO4 buffer by SPR analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA3624737 | B | Binding affinity to Grb7-SH2 domain (unknown origin) without using phosphate buffer by SPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3624738 | B | Binding affinity to Grb7-SH2 domain (unknown origin) using 100 mM phosphate buffer by SPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4032099 | B | Inhibition of GRB7-FAK interaction in human SKBR3 cells assessed as FAK detection in cell lysates at 20 uM preincubated for 1 hr followed by fibronectin stimulation measured after 10 mins by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4032100 | B | Binding affinity to human GST-tagged GRB7-SH2 domain (415 to 594 residues) expressed in Escherichia coli BL21(DE3) pLys after 60 to 80 secs in presence of 50 mM phosphate buffer by SPR assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 14. | ALA4032101 | B | Binding affinity to human GST-tagged GRB7-SH2 domain (415 to 594 residues) expressed in Escherichia coli BL21(DE3) pLys after 60 to 80 secs in presence of 1 mM phosphate buffer by SPR assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 15. | ALA4032102 | B | Ratio of Kd in presence of 1 mM sodium phosphate buffer to Kd in presence of 50 mM sodium phosphate buffer for GST-tagged GRB7-SH2 (415 to 532 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4032103 | B | Ratio of Kd in presence of 1 mM sodium phosphate buffer to Kd in presence of 50 mM sodium phosphate buffer for human GST-tagged GRB7-SH2 domain (415 to 594 residues) expressed in Escherichia coli BL21(DE3) pLys | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA4032106 | B | Inhibition of GRB7-SHC interaction in human SKBR3 whole cells at 20 uM preincubated for 1 hr followed by fibronectin stimulation measured after 10 mins by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4032107 | B | Inhibition of GRB7-HER2 interaction in human SKBR3 cells assessed as HER2 detection in whole cells at 20 uM preincubated for 1 hr followed by fibronectin stimulation measured after 10 mins by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4032108 | B | Inhibition of GRB7-FAK interaction in human SKBR3 cells assessed as FAK detection in whole cells at 20 uM preincubated for 1 hr followed by fibronectin stimulation measured after 10 mins by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA4032109 | B | Inhibition of GRB7-HER2 interaction in human SKBR3 cells assessed as HER2 detection in cell lysates at 20 uM preincubated for 1 hr followed by fibronectin stimulation measured after 10 mins by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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