# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1647668 | B | Inhibition of MCP1-mediated human THP cell migration | Homo sapiens | 4 | ALA1641363 | cell-based format | Scientific Literature | |
2. | ALA2428936 | B | Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes assessed as association and dissociation of compound by competition association assay | Homo sapiens | 1 | ALA2424582 | cell-based format | Scientific Literature | |
3. | ALA2428937 | B | Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes assessed as association and dissociation of radioligand | Homo sapiens | 1 | ALA2424582 | cell-based format | Scientific Literature | |
4. | ALA2428938 | B | Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes | Homo sapiens | 1 | ALA2424582 | cell-based format | Scientific Literature | |
5. | ALA2428939 | B | Displacement of [3H]INCB3344 from human CCR2 receptor expressed in human U2OS cell membranes by saturation binding assay | Homo sapiens | 1 | ALA2424582 | cell-based format | Scientific Literature | |
6. | ALA2428940 | B | Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membrane assessed as residence time | Homo sapiens | 7 | ALA2424582 | cell-based format | Scientific Literature | |
7. | ALA2428941 | B | Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membrane assessed as kinetic rate index at Ki by dual-point competition association assay relative to control | Homo sapiens | 15 | ALA2424582 | cell-based format | Scientific Literature | |
8. | ALA2428942 | B | Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membrane at 1 uM relative to control | Homo sapiens | 6 | ALA2424582 | cell-based format | Scientific Literature | |
9. | ALA2428943 | B | Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranes | Homo sapiens | 22 | ALA2424582 | cell-based format | Scientific Literature | |
10. | ALA3227324 | B | Inhibition of CCL2 in human THP1 cells assessed as effect on level of ERK1/2 phosphorylation at 50 uM after 5 mins by Western blot analysis | Homo sapiens | 2 | ALA3217544 | cell-based format | Scientific Literature | |
11. | ALA3227325 | B | Inhibition of CCL2 in human PBMC assessed as reduction of cell adhesion to VCAM1-Fc at 50 uM by flow based adhesion assay | Homo sapiens | 1 | ALA3217544 | single protein format | Scientific Literature | |
12. | ALA3227328 | B | Inhibition of CCL2 in human PBMC assessed as reduction of cell migration into TNFalpha/IFNgamma-stimulated HMEC-1 cells at 50 uM after 4 hrs | Homo sapiens | 2 | ALA3217544 | cell-based format | Scientific Literature | |
13. | ALA3225876 | B | Inhibition of CCL2 in human THP1 cells assessed as reduction of cell migration into TNFalpha/IFNgamma-stimulated HMEC-1 cells at 50 uM after 4 hrs | Homo sapiens | 2 | ALA3217544 | cell-based format | Scientific Literature | |
14. | ALA3225877 | B | Inhibition of CCL2 in human THP1 cells assessed as reduction of cell migration at 100 uM after 3 hrs | Homo sapiens | 2 | ALA3217544 | cell-based format | Scientific Literature | |
15. | ALA3225878 | B | Inhibition of CCL2 in human THP1 cells assessed as reduction of cell migration at 50 uM after 3 hrs | Homo sapiens | 2 | ALA3217544 | cell-based format | Scientific Literature | |
16. | ALA3293903 | B | Binding affinity to human recombinant CCL2 by surface plasmon resonance assay | Homo sapiens | 3 | ALA3286317 | single protein format | Scientific Literature | |
17. | ALA4152016 | B | Binding affinity to CCL2 (unknown origin) assessed as inhibition of CXCL12 -induced increase in intracellular calcium level in EGFP-tagged CCR2 expressing HEK cells at 10 uM | Homo sapiens | 1 | ALA4145692 | cell-based format | Scientific Literature | |
18. | ALA4885692 | B | In vitro inhibition of MCP-1 in Lipopolysaccharide-stimulated human whole blood | Homo sapiens | 1 | ALA4630905 | tissue-based format | Donated Chemical Probes - SGC Frankfurt | |
19. | ALA4885695 | B | LPS-PBMC assay (MCP-1) | Homo sapiens | 1 | ALA4630905 | single protein format | Donated Chemical Probes - SGC Frankfurt | |
20. | ALA4885758 | B | In vitro inhibition of MCP-1 in Lipopolysaccharide-stimulated human whole blood | Homo sapiens | 1 | ALA4630908 | tissue-based format | Donated Chemical Probes - SGC Frankfurt |