# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1175118 | B | Inhibition of VRK2 at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
2. | ALA1646680 | B | Inhibition of human VRK2 at 10 uM after 60 mins by TR-FRET assay | Homo sapiens | 1 | ALA1641539 | single protein format | Scientific Literature | |
3. | ALA1908755 | B | Binding constant for VRK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
4. | ALA2219325 | B | Millipore: Percentage of residual kinase activity of VRK2 at 1uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA | Homo sapiens | 158 | ALA2218924 | single protein format | Scientific Literature | |
5. | ALA2219326 | B | Millipore: Percentage of residual kinase activity of VRK2 at 10uM relative to control. Control inhibitor: Phosphoric acid* at 0.3uM. Buffer: 8 mM MOPS pH 7.0, 0.2 mM EDTA | Homo sapiens | 158 | ALA2218924 | single protein format | Scientific Literature | |
6. | ALA2345760 | B | Inhibition of VRK2 (unknown origin) | Homo sapiens | 1 | ALA2331117 | single protein format | Scientific Literature | |
7. | ALA3100756 | B | Inhibition of human VRK2 assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3098105 | single protein format | Scientific Literature | |
8. | ALA3240773 | B | Inhibition of human VRK2 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
9. | ALA3430846 | B | Delta TM value showing the stabilisation of VRK2 produced by compound binding | Homo sapiens | 156 | ALA1145498 | single protein format | Scientific Literature | |
10. | ALA3631622 | B | Inhibition of VRK2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
11. | ALA3749902 | B | Inhibition of human VRK2 using casein as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
12. | ALA3779063 | B | Inhibition of N-terminal His6-tagged recombinant human VRK2 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
13. | ALA3864838 | B | Competitive binding affinity to partial length wild type human VRK2 expressed in mammalian expression system at 10 uM by kinomescan method relative to control | Homo sapiens | 1 | ALA3864151 | assay format | Scientific Literature | |
14. | ALA4025435 | B | Inhibition of wild-type human partial length VRK2 (M1 to T336 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
15. | ALA4034514 | B | Inhibition of VRK2 Lysine 2 labelling site (unknown origin) at 10 uM | Homo sapiens | 1 | ALA4033637 | single protein format | Scientific Literature | |
16. | ALA4044246 | B | Inhibition of wild-type human partial length VRK2 (M1 to T336 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
17. | ALA4054985 | B | Inhibition of wild-type human partial length VRK2 (M1 to T336 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
18. | ALA4118490 | B | Inhibition of VRK2 in human SKCO1 cells at 1 uM after 4 hrs using biotin labeled MLDVLEYIHENEYVHGDIKAANLLLYK probe by mass-spectrometric analysis relative to control | Homo sapiens | 3 | ALA4118021 | cell-based format | Scientific Literature | |
19. | ALA4157325 | B | Binding affinity to wild-type human partial length VRK2 (M1 to T336 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
20. | ALA4186104 | B | Binding affinity to wild-type human partial length VRK2 (M1 to T336 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature |