# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1667299 | B | Inhibition of Influenza A virus (A/Turkey/651242/2006(H5N1)) neuraminidase by fluorometric assay | Influenza A virus (A/Turkey/651242/2006(H5N1)) | 2 | ALA1649470 | single protein format | Scientific Literature | |
2. | ALA1665839 | B | Inhibition of Influenza A virus (A/Turkey/651242/2006(H5N1)) neuraminidase by Michaelis-Menten equation analysis | Influenza A virus (A/Turkey/651242/2006(H5N1)) | 2 | ALA1649470 | single protein format | Scientific Literature | |
3. | ALA3390208 | B | Inhibition of Influenza A virus A/chicken/china/1220/2012(H5N1) Neuraminidase N1 | Influenza A virus | 35 | ALA3352529 | single protein format | Scientific Literature | |
4. | ALA3381801 | B | Ratio of oseltamivir carboxylate IC50 to compound IC50 for Influenza A virus A/chicken/china/1220/2012(H5N1) Neuraminidase N1 | Influenza A virus | 1 | ALA3352529 | single protein format | Scientific Literature | |
5. | ALA3381803 | B | Binding affinity to Influenza A virus H5N1 Neuraminidase N1 | Influenza A virus | 1 | ALA3352529 | single protein format | Scientific Literature | |
6. | ALA3381805 | B | Binding affinity to Influenza A virus H3N2 Neuraminidase N1 | Influenza A virus | 1 | ALA3352529 | single protein format | Scientific Literature | |
7. | ALA3381806 | B | Inhibition of Influenza A virus H1N1 Neuraminidase N1 | Influenza A virus | 1 | ALA3352529 | single protein format | Scientific Literature | |
8. | ALA3382393 | B | Inhibition of Influenza A virus H3N2 Neuraminidase N1 | Influenza A virus | 1 | ALA3352529 | single protein format | Scientific Literature | |
9. | ALA3420075 | B | Inhibition of Influenza A virus (H5N1) neuraminidase N1 at 20 microg/ml after 30 mins by fluorescence based assay | Influenza A virus | 3 | ALA3414427 | single protein format | Scientific Literature | |
10. | ALA4120974 | B | Inhibition of Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) clade 2 neuraminidase activity using 4-MUNANA as substrate preincubated for 60 mins followed by substrate addition measured every min for 60 mins by fluorescence assay | Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
11. | ALA4120975 | B | Inhibition of Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) clade 2 neuraminidase activity using 4-MUNANA as substrate measured every min for 60 mins by fluorescence assay | Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
12. | ALA4120991 | B | Inhibition of Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) clade 2 neuraminidase activity using 4-MUNANA as substrate assessed as reactivation half life by measuring reaction rate to reach 50% of maximum rate of uninhibited control after removal of inhibitor preincubated for 30 mins followed by compound washout and subsequent substrate addition measured after each 10 mins for 4 hrs by fluorescence assay (Rvb = 12.1 +/- 1.0 min) | Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
13. | ALA4121005 | B | Ratio of IC50 for Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) clade 2 neuraminidase measured every min for 60 mins to IC50 for Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) clade 2 neuraminidase preincubated for 60 mins followed by substrate addition measured every min for 60 mins | Influenza A virus (A/chicken/Bangli/BBVD-563/2007(H5N1)) | 6 | ALA4118102 | single protein format | Scientific Literature | |
14. | ALA4252155 | B | Inhibition of Influenza A virus A/Anhui/1/2005(H5N1) neuraminidase at 10 uM using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition measured after 30 mins by fluorescence assay relative to control | Influenza A virus (A/Anhui/1/2005(H5N1)) | 14 | ALA4251557 | single protein format | Scientific Literature | |
15. | ALA4252156 | B | Inhibition of Influenza A virus A/Anhui/1/2005(H5N1) neuraminidase at 100 uM using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition measured after 30 mins by fluorescence assay relative to control | Influenza A virus (A/Anhui/1/2005(H5N1)) | 14 | ALA4251557 | single protein format | Scientific Literature | |
16. | ALA4252161 | B | Inhibition of Influenza A virus A/Anhui/1/2005(H5N1) neuraminidase using MUNANA as substrate preincubated for 5 to 15 mins followed by substrate addition measured after 30 mins by fluorescence assay | Influenza A virus (A/Anhui/1/2005(H5N1)) | 8 | ALA4251557 | single protein format | Scientific Literature | |
17. | ALA4254781 | B | Inhibition of Influenza A virus (A/Vietnam/1194/2004 (H5N1)) recombinant neuraminidase expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometry | Influenza A virus (A/Vietnam/1194/2004(H5N1)) | 3 | ALA4251642 | cell-based format | Scientific Literature | |
18. | ALA4254782 | B | Inhibition of Influenza A virus (A/Vietnam/1194/2004 (H5N1)) recombinant neuraminidase H275Y mutant expressed in HEK293 cells pre-incubated for 10 mins before 4-MUNANA substrate addition by fluorometry | Influenza A virus (A/Vietnam/1194/2004(H5N1)) | 3 | ALA4251642 | cell-based format | Scientific Literature | |
19. | ALA4276518 | B | Inhibition of Influenza A virus A/Anhui/1/2005(H5N1) neuraminidase N1 H274Y mutant using fluorogenic MUNANA as substrate preincubated for 10 mins followed by substrate addition measured after 40 to 60 mins by fluorescence-based assay | Influenza A virus | 13 | ALA4270670 | single protein format | Scientific Literature |