# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1670746 | Binding | Inhibition of human Ero1-Lalpha | Homo sapiens | 12 | ALA1667849 | single protein format | Scientific Literature | |
2. | ALA4321224 | Binding | Competitive inhibition of recombinant human Ero1Lalpha C104A/C131A/C166A triple mutant (22 to 468 residues) expressed in Escherichia coli BL21(DE3)-RIL using varying levels of human PDI as substrate by Lineweaver-burk plot analysis | Homo sapiens | 1 | ALA4316617 | assay format | Scientific Literature | |
3. | ALA4321230 | Binding | Inhibition of recombinant human Ero1Lalpha C104A/C131A/C166A triple mutant (22 to 468 residues) expressed in Escherichia coli BL21(DE3)-RIL measured after 30 mins by Amplex red dye based fluorescence assay | Homo sapiens | 4 | ALA4316617 | assay format | Scientific Literature | |
4. | ALA4321232 | Binding | Binding affinity to recombinant human Ero1Lalpha C104A/C131A/C166A triple mutant (22 to 468 residues) expressed in Escherichia coli BL21(DE3)-RIL assessed as melting temperature at 20 uM by SYPRO orange protein gel staining based differential scanning fluorimetry (Rvb = 53.15 +/- 0.15 degreeC) | Homo sapiens | 2 | ALA4316617 | assay format | Scientific Literature | |
5. | ALA4321240 | Binding | Inhibition of recombinant human Ero1Lalpha C104A/C131A/C166A triple mutant (22 to 468 residues) expressed in Escherichia coli BL21(DE3)-RIL using human PDI as substrate measured after 30 mins by Amplex red dye based fluorescence assay | Homo sapiens | 1 | ALA4316617 | assay format | Scientific Literature |