| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1218539 | B | Binding affinity to Escherichia coli K-12 MC1061 acrB assessed as decrease in susceptibility to compound efflux at 2 to 128 ug/ml after 16 hrs by plate reader assay | Escherichia coli K-12 | 1 | ALA1212733 | single protein format | Scientific Literature | |
| 2. | ALA1218540 | B | Binding affinity to Escherichia coli K-12 MC1061 acrB assessed as susceptibility to compound efflux at 0.01 to 1 ug/ml after 16 hrs by plate reader assay | Escherichia coli K-12 | 1 | ALA1212733 | single protein format | Scientific Literature | |
| 3. | ALA1681169 | B | Binding affinity to Escherichia coli K-12 multidrug efflux protein AcrB at pH 8.4 by equilibrium dialysis method | Escherichia coli K-12 | 1 | ALA1671618 | single protein format | Scientific Literature | |
| 4. | ALA4424811 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of chloramphenicol-induced antimicrobial activity by measuring chloramphenicol MIC at 8 ug/ml by checkerboard titration method (Rvb =16 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 5. | ALA4424812 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of chloramphenicol-induced antimicrobial activity by measuring chloramphenicol MIC at 16 ug/ml by checkerboard titration method (Rvb =16 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 6. | ALA4424813 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of chloramphenicol-induced antimicrobial activity by measuring chloramphenicol MIC at 32 ug/ml by checkerboard titration method (Rvb =16 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 7. | ALA4424814 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of chloramphenicol-induced antimicrobial activity by measuring chloramphenicol MIC at 64 ug/ml by checkerboard titration method (Rvb =16 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 8. | ALA4424815 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of chloramphenicol-induced antimicrobial activity by measuring chloramphenicol MIC at 128 ug/ml by checkerboard titration method (Rvb =16 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 9. | ALA4424816 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of erythromycin-induced antimicrobial activity by measuring erythromycin MIC at 8 ug/ml by checkerboard titration method (Rvb = 64 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 10. | ALA4424817 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of erythromycin-induced antimicrobial activity by measuring erythromycin MIC at 16 ug/ml by checkerboard titration method (Rvb = 64 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 11. | ALA4424818 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of erythromycin-induced antimicrobial activity by measuring erythromycin MIC at 32 ug/ml by checkerboard titration method (Rvb = 64 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 12. | ALA4424819 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of erythromycin-induced antimicrobial activity by measuring erythromycin MIC at 64 ug/ml by checkerboard titration method (Rvb = 64 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 13. | ALA4424820 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of erythromycin-induced antimicrobial activity by measuring erythromycin MIC at 128 ug/ml by checkerboard titration method (Rvb = 64 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 14. | ALA4424821 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of tetraphenyl phosphonium chloride-induced antimicrobial activity by measuring tetraphenyl phosphonium chloride MIC at 8 ug/ml by checkerboard titration method (Rvb = 1024 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 15. | ALA4424822 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of tetraphenyl phosphonium chloride-induced antimicrobial activity by measuring tetraphenyl phosphonium chloride MIC at 16 ug/ml by checkerboard titration method (Rvb = 1024 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 16. | ALA4424823 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of tetraphenyl phosphonium chloride-induced antimicrobial activity by measuring tetraphenyl phosphonium chloride MIC at 32 ug/ml by checkerboard titration method (Rvb = 1024 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 17. | ALA4424824 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of tetraphenyl phosphonium chloride-induced antimicrobial activity by measuring tetraphenyl phosphonium chloride MIC at 64 ug/ml by checkerboard titration method (Rvb = 1024 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 18. | ALA4424825 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of tetraphenyl phosphonium chloride-induced antimicrobial activity by measuring tetraphenyl phosphonium chloride MIC at 128 ug/ml by checkerboard titration method (Rvb = 1024 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 19. | ALA4424826 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of levofloxacin-induced antimicrobial activity by measuring levofloxacin MIC at 8 ug/ml by checkerboard titration method (Rvb = 0.063 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature | |
| 20. | ALA4424827 | B | Inhibition of AcrB in wild-type drug-resistant Escherichia coli BW2113 assessed as potentiation of levofloxacin-induced antimicrobial activity by measuring levofloxacin MIC at 16 ug/ml by checkerboard titration method (Rvb = 0.063 ug/ml) | Escherichia coli | 12 | ALA4422685 | single protein format | Scientific Literature |
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