# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1738194 | B | PUBCHEM_BIOASSAY: C-LANA FP assay Measured in Biochemical System Using Plate Reader - 2117-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504431] | Human gammaherpesvirus 8 | 201 | ALA1201862 | biochemical format | PubChem BioAssays | |
2. | ALA1738200 | F | PUBCHEM_BIOASSAY: Luminescent Cell-Based Counter Screen to Identify Non-Cytotoxic Compounds. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2629, AID2659] | Human gammaherpesvirus 8 | 35 | ALA1201862 | cell-based format | PubChem BioAssays | |
3. | ALA1794405 | B | PUBCHEM_BIOASSAY: Fluorescence Polarization Biochemical Secondary LANA-Nucleosome Assay_2053_04_Inhibitor_Dose_DryPowder_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2659] | ⋯ | ALA1201862 | single protein format | PubChem BioAssays | ||
4. | ALA4385774 | B | Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 25 | ALA4385596 | assay format | Scientific Literature | |
5. | ALA4385775 | B | Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 1 mM preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay relative to control | Human gammaherpesvirus 8 | 20 | ALA4385596 | assay format | Scientific Literature | |
6. | ALA4385776 | B | Inhibition of fluorescent labelled LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay relative to control | Human gammaherpesvirus 8 | 1 | ALA4385596 | assay format | Scientific Literature | |
7. | ALA4385777 | B | Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
8. | ALA4385778 | B | Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
9. | ALA4385779 | B | Inhibition of 5'-Dy682-labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
10. | ALA4385780 | B | Binding affinity to human herpesvirus human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) by microscale thermophoresis assay | Human gammaherpesvirus 8 | 1 | ALA4385596 | assay format | Scientific Literature | |
11. | ALA4385781 | B | Inhibition of 5'-Dy682-labelled LBS1/LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay | Human gammaherpesvirus 8 | 6 | ALA4385596 | assay format | Scientific Literature | |
12. | ALA4385783 | B | Inhibition of 5'-Dy682-labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay | Human gammaherpesvirus 8 | 1 | ALA4385596 | assay format | Scientific Literature | |
13. | ALA4385785 | B | Binding affinity to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 1 mM by STD-NMR analysis | Human gammaherpesvirus 8 | 1 | ALA4385596 | assay format | Scientific Literature |