# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA768693 | B | Effective concentration against Potassium voltage gated channel KQT-like subfamily, member 2 expressed in HEK 293 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA768694 | B | Effective concentration against Potassium voltage gated channel, KQT-like subfamily, member 2 expressed in SH-SY5Y human neuroblastoma cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA2071938 | B | Activation of KCNQ2 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2071942 | B | Activation of KCNQ2 channel expressed in CHO cells assessed as depolarization-induced thallium influx up to 30 uM after 3 mins by patch clamp assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA925894 | B | Inhibition of KCNQ2 channel | 1 | single protein format | Scientific Literature | |||
6. | ALA926131 | B | Activity at Kv 7.2 channel expressed in cloned CHO cells by [86Rb] efflux assay | 1 | cell-based format | Scientific Literature | |||
7. | ALA2169530 | F | Agonist activity at KCNQ2 expressed in CHO cells at 30 uM incubated for 3 mins by automated patch clamp assay | 1 | cell-based format | Scientific Literature | |||
8. | ALA2169531 | F | Antagonist activity at KCNQ2 expressed in CHO cells at 30 uM incubated for 3 mins by automated patch clamp assay | 6 | cell-based format | Scientific Literature | |||
9. | ALA2169532 | F | Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay | 24 | cell-based format | Scientific Literature | |||
10. | ALA2169533 | F | Antagonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay | 34 | cell-based format | Scientific Literature | |||
11. | ALA2168495 | B | Inhibition of KCNQ2 at 10 uM | 1 | single protein format | Scientific Literature | |||
12. | ALA2168500 | B | Inhibition of KCNQ2 | 1 | single protein format | Scientific Literature | |||
13. | ALA2327425 | B | Positive modulatory activity at voltage-gated K channel 7.2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA3367863 | B | Inhibition of KCNQ2 (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature | ||
15. | ALA4122313 | B | Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM incubated for 20 mins in dark measured every 2 secs for 10 secs by fluorescence-based thallium influx assay relative to control | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
16. | ALA4122314 | B | Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM incubated for 20 mins in dark measured every 2 secs for 10 secs by fluorescence-based thallium influx assay relative to retigabine | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
17. | ALA4122315 | B | Activation of KCNQ2 (unknown origin) expressed in CHO cells at 10 uM after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
18. | ALA4122316 | B | Activation of KCNQ2 (unknown origin) expressed in CHO cells assessed as conductivity (I/I0) at 10 uM by electrophysiological patch-clamp test | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
19. | ALA4122317 | B | Activation of KCNQ2 (unknown origin) expressed in CHO cells assessed as half-maximum activation voltage left shift at 10 uM by electrophysiological patch-clamp test | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
20. | ALA4235019 | B | Channel opening activity at KCNQ2 (unknown origin) expressed in CHO cells after 10 mins by atomic absorption spectrophotometry-based Rb+ flow assay | Homo sapiens | 13 | cell-based format | Scientific Literature |