| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3616266 | Binding | Inhibition of APOBEC3A (unknown origin) by fluorescence-based ssDNA C-to-U deaminase assay | Homo sapiens | 1 | ALA3612064 | single protein format | Scientific Literature | |
| 2. | ALA1738027 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493011, AID493024] | Homo sapiens | 448 | ALA1201862 | assay format | PubChem BioAssays | |
| 3. | ALA1737903 | Functional | PUBCHEM_BIOASSAY: Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493012, AID493028] | Homo sapiens | 284 | ALA1201862 | assay format | PubChem BioAssays | |
| 4. | ALA1964060 | Functional | PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay. (Class of assay: confirmatory) | 98 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA1963851 | Functional | PUBCHEM_BIOASSAY: SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2. (Class of assay: confirmatory) | 42 | ALA1201862 | assay format | PubChem BioAssays | ||
| 6. | ALA4419751 | Binding | Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay | Homo sapiens | 11 | ALA4419174 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4419755 | Binding | Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs and measured on day 0 by fluorescence-based assay | Homo sapiens | 1 | ALA4419174 | cell-based format | Patent Bioactivity Data | |
| 8. | ALA4419766 | Binding | Inhibition of recombinant APOBEC3A (unknown origin) expressed in HEK293 cells assessed as reduction in cytosine deaminase activity at 200 uM using 5'-6-FAM and 3'-TAMRA quench molecule tagged cytosine-containing single-stranded DNA substrate incubated for 2 hrs by fluorescence-based assay relative to control | Homo sapiens | 1 | ALA4419174 | cell-based format | Patent Bioactivity Data |
The page will load shortly, Thanks for your patience!