| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1908084 | A | Specific activity of expressed human recombinant UGT1A7 | Homo sapiens | 48 | single protein format | Scientific Literature | ||
| 2. | ALA1908118 | B | Drug glucuronidation reaction catalyzed by human recombinant UGT1A7 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA1908128 | B | Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A7 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 4. | ALA1743328 | A | Substrate of human UDP-glucuronosyltransferase UGT1A7 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 5. | ALA3541114 | A | Activity of human UGT1A7 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated (2S,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(5-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)benzyl)-2,4-dioxothiazolidin-3-yl)tetrahydro-2H-pyran-2-carboxylic acid formation at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of UDPGA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA3539910 | A | Drug metabolism assessed as recombinant human UGT1A7 assessed as O-glucuronidation at 100 uM incubated for 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3539920 | A | Drug metabolism assessed as recombinant human UGT1A7 assessed as N-glucuronidation at 100 uM incubated for 60 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3537408 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT1A7-mediated 17-epiestriol-3-glucuronide formation at 200 uM after 15 to 60 mins by HPLC analysis in presence of UDPGA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3538804 | A | Drug metabolism assessed as human UGT1A7-mediated N-glucuronide-triclocarban formation expressed in baculovirus infected insect sf9 cells incubated for 5 mins prior to UDPGA addition measured after 5 to 30 mins by LC-UV analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3541446 | A | Activity of human recombinant UGT1A7 expressed in insect cells assessed as enzyme mediated glucuronidation at 500 uM by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3541755 | A | Drug metabolism assessed as human UGT1A7-mediated N'-glucuronide-triclocarban formation expressed in baculovirus infected insect sf9 cells incubated for 5 mins prior to UDPGA addition measured after 5 to 30 mins by LC-UV analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3534351 | A | Activity of human recombinant UGT1A7 expressed in baculovirus-infected insect cells assessed as enzyme-mediated glucuronidation per mg of protein after 10 mins in presence of UDPGA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3534360 | A | Activity of human recombinant UGT1A7 expressed in baculovirus-infected insect cells assessed as enzyme-mediated glucuronidation after 10 mins by Michaelis-Menten plot analysis in presence of UDPGA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3534361 | A | Activity of human recombinant UGT1A7 expressed in baculovirus-infected insect cells assessed as enzyme-mediated glucuronidation per mg of protein after 10 mins by Michaelis-Menten plot analysis in presence of UDPGA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3534362 | A | Activity of human recombinant UGT1A7 expressed in baculovirus-infected insect cells assessed as intrinsic clearance for enzyme-mediated glucuronide formation per mg of protein at 1 to 250 uM after 10 mins by Michaelis-Menten plot analysis in presence of UDPGA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3531818 | A | Activity of human recombinant UGT1A7 expressed in insect cells assessed as enzyme mediated glucuronidation at 12.5 uM by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3531839 | A | Activity of human recombinant UGT1A7 expressed in insect cells assessed as enzyme mediated glucuronidation by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3531840 | A | Activity of human recombinant UGT1A7 expressed in insect cells assessed as enzyme mediated glucuronidation per mg protein by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3531841 | A | Activity of human recombinant UGT1A7 expressed in insect cells assessed as intrinsic clearance for enzyme mediated glucuronidation per mg protein by LC-MS/MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3532971 | A | Drug metabolism assessed as recombinant human C-terminal His-tagged UGT1A7-mediated 16-epiestriol-3-glucuronide formation after 15 to 60 mins by Michaelis-Menten equation analysis in presence of UDPGA | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!