| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1175219 | B | Inhibition of PIP5K2C at 10 uM | 2 | single protein format | Scientific Literature | |||
| 2. | ALA1219797 | B | Inhibition of PIP5K2C at 1 uM by radiometric method | 2 | single protein format | Scientific Literature | |||
| 3. | ALA1772044 | B | Binding affinity to human PIP5K2C | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 4. | ALA1908831 | B | Binding constant for PIP5K2C kinase domain | 72 | single protein format | Scientific Literature | |||
| 5. | ALA1942474 | B | Inhibition of human PIP4K2C in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA2211988 | B | Inhibition of PIP4K2C | 1 | single protein format | Scientific Literature | |||
| 7. | ALA2212494 | B | Inhibition of PIP5K2C assessed as residual activity at 10 uM relative to control | 1 | single protein format | Scientific Literature | |||
| 8. | ALA2394162 | B | Competitive binding affinity to PIP5K2C (unknown origin) assessed as enzyme remaining bound to anchored active-site ligand at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA2424040 | B | Inhibition of PIP4K2C in human PC3 cell lysates at 10 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 10. | ALA2424254 | B | Inhibition of PIP4K2C in human PC3 cell lysates at 30 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA3111942 | B | Inhibition of PIP5K2C (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3624245 | B | Inhibition of PIP5K2C (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3734155 | B | Inhibition of PIP5K2C (unknown origin) | Homo sapiens | 75 | single protein format | Patent Bioactivity Data | ||
| 14. | ALA3826093 | B | Inhibition of partial length human wild type PIP5K2C (M1 to A421 residues) expressed in mammalian expression system at 1 uM by KINOMEScan assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA3855903 | B | Inhibition of human PIP5K2C (M1 to A421 residues) expressed at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3862733 | B | Binding affinity to human PIP5K2C expressed in Escherichia coli BL21 cells incubated for 1 hr by active site directed binding competition assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3991828 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 240 | subcellular format | Kuster lab chemical proteomics drug profiling | ||
| 18. | ALA4015994 | B | Inhibition of PIPK2C in human THP1 cell lysate at 200 nM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4025327 | B | Inhibition of wild-type human partial length PIP5K2C (M1 to A421 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4031764 | B | Binding affinity to PIP4K2C in human HCT116 cell lysate at 3 uM after 1 hr by LC-MS/MS analysis | Homo sapiens | 1 | assay format | Scientific Literature |
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