# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1772337 | F | Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium release by FLIPR assay | Mus musculus | 44 | ALA1770138 | cell-based format | Scientific Literature | |
2. | ALA1772397 | F | Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium release at 20 uM by FLIPR assay | Mus musculus | 3 | ALA1770138 | cell-based format | Scientific Literature | |
3. | ALA1776795 | F | Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Mus musculus | 21 | ALA1773017 | cell-based format | Scientific Literature | |
4. | ALA4349431 | B | Inhibition of mouse P2Y14 receptor | Mus musculus | 2 | ALA4346722 | single protein format | Scientific Literature | |
5. | ALA4349437 | B | Inhibition of mouse P2Y14 receptor in presence of 2% HSA | Mus musculus | 2 | ALA4346722 | single protein format | Scientific Literature | |
6. | ALA4619168 | B | Displacement of Alexafluor488 labeled 4-(4-(1-(4-(1-(6-(4-(6-amino-3-imino-4,5-disulfo-3H-xanthen-9-yl)-3-carboxybenzamido)hexyl)-1H-1,2,3-triazol-4-yl)butyl)piperidin-4-yl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid from HA-tagged mouse P2Y14 expressed in HEK293 cells measured after 30 mins by FACScalibur flow cytometry analysis | Mus musculus | 8 | ALA4616709 | cell-based format | Scientific Literature | |
7. | ALA4622294 | B | Inhibition of MRS4174 binding to mouse P2Y14R expressed in HEK293 cells pre-incubated for 30 mins before MRS4174 addition and further incubated for 30 mins by flow cytomtery based competitive fluorescence assay | Mus musculus | 13 | ALA4619807 | cell-based format | Scientific Literature | |
8. | ALA4808687 | B | Inhibition of fluorescent antagonist binding to mouse P2Y14 receptor expressed in HEK293 cells preincubated with compound for 30 mins followed by fluorescent antagonist addition and measured after 30 mins by flow cytometry analysis | Mus musculus | 4 | ALA4808172 | cell-based format | Scientific Literature | |
9. | ALA5045604 | B | Inhibition of fluorescent antagonist binding to mouse P2Y14R expressed in HEK293 cells preincubated for 30 mins followed by addition of 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy-6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate incubated for 30 mins by BD FACSCalibur flow cytometry analysis | Mus musculus | 10 | ALA5042543 | cell-based format | Scientific Literature |