# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1776262 | B | Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay | Mycobacterium tuberculosis | 8 | ALA1773054 | single protein format | Scientific Literature | |
2. | ALA1947973 | B | Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assay | 6 | ALA1944547 | single protein format | Scientific Literature | ||
3. | ALA1947974 | B | Inhibition of Mycobacterium tuberculosis H37Rv EthR in Mycobacterium tuberculosis H37Rv expressing GFP infected mouse in RAW264.7 cells assessed as potentiation of ethionamide-induced antitubercular activity after 5 days by SYTO60-based fluorescence microscopy | Mycobacterium tuberculosis H37Rv | 41 | ALA1944547 | cell-based format | Scientific Literature | |
4. | ALA2169624 | B | Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as boosting of 0.1 uM ethionamide-induced microbial growth inhibition at 10 uM by automated fluorescent confocal microscopy | Mycobacterium tuberculosis H37Rv | 24 | ALA2163226 | cell-based format | Scientific Literature | |
5. | ALA2169625 | B | Inhibition of EthR in Mycobacterium tuberculosis H37Rv-GFP infected in mouse Raw 264.7 cells assessed as compound concentration allowing 0.1 uM ethionamide to inhibit 50% microbial growth by automated fluorescent confocal microscopy | Mycobacterium tuberculosis H37Rv | 6 | ALA2163226 | cell-based format | Scientific Literature | |
6. | ALA4232685 | B | Inhibition of Mycobacterium tuberculosis EthR | Mycobacterium tuberculosis | 1 | ALA4229404 | single protein format | Scientific Literature | |
7. | ALA4391036 | B | Binding affinity to Mycobacterium tuberculosis EthR at 30 uM by mammalian reporter assay | Mycobacterium tuberculosis | 1 | ALA4390646 | single protein format | Scientific Literature | |
8. | ALA4434519 | B | Inhibition of Mycobacterium tuberculosis H37Rv EthR | Mycobacterium tuberculosis H37Rv | 1 | ALA4433260 | single protein format | Scientific Literature |