# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1072193 | B | Inhibition of BUB1 | 3 | ALA1157561 | single protein format | Scientific Literature | ||
2. | ALA1776517 | B | Inhibition of BUB1 assessed as [33P]gamma-ATP incorporation into substrate after 60 mins by gamma counting | 1 | ALA1773059 | single protein format | Scientific Literature | ||
3. | ALA2209761 | B | Inhibition of BUB1 assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
4. | ALA3112120 | B | Inhibition of BUB1 (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
5. | ALA3271320 | B | Inhibition of Bub1 kinase (unknown origin) by TR-FRET kinase assay | Homo sapiens | 6 | ALA3259793 | single protein format | Scientific Literature | |
6. | ALA3301289 | B | Inhibition of BUB1 (unknown origin) | Homo sapiens | 2 | ALA3297733 | single protein format | Scientific Literature | |
7. | ALA3381062 | B | Inhibition of BUB1 (unknown origin) | Homo sapiens | 5 | ALA3352169 | single protein format | Scientific Literature | |
8. | ALA3419151 | B | Competitive binding affinity to human BUB1 | Homo sapiens | 1 | ALA3414433 | single protein format | Scientific Literature | |
9. | ALA3607951 | B | Inhibition of human BUB1 | Homo sapiens | 1 | ALA3603755 | single protein format | Scientific Literature | |
10. | ALA3768601 | B | Inhibition of human BUB1 | Homo sapiens | 1 | ALA3763144 | single protein format | Scientific Literature | |
11. | ALA3991639 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 220 | ALA3991601 | subcellular format | Kuster lab chemical proteomics drug profiling | |
12. | ALA4025034 | B | Inhibition of wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
13. | ALA4043845 | B | Inhibition of wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
14. | ALA4156924 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
15. | ALA4185703 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature | |
16. | ALA4230603 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
17. | ALA4264192 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature | |
18. | ALA4307709 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4304811 | assay format | Scientific Literature | |
19. | ALA4357781 | B | Binding affinity to wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4354843 | assay format | Scientific Literature | |
20. | ALA4365627 | B | Inhibition of wild-type human partial length BUB1 (Q724 to K1085 residues) expressed in mammalian expression system assessed as residual activity at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4364269 | assay format | Scientific Literature |