| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1212457 | B | Inhibition of mouse TRPV1 receptor | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 2. | ALA1786054 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux by fluorometric analysis | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 3. | ALA1786676 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux at 125 uM after 5 mins by fluorometric analysis in presence of at 25 mM of KCl | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA1786682 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux at 125 uM after 3 hrs by fluorometric analysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 5. | ALA1786683 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux at 125 uM after 3 hrs by fluorometric analysis in presence of 10 ug/ml translational inhibitor cycloheximide | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 6. | ALA1786684 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux at 125 uM after 3 hrs by fluorometric analysis in presence of 5.6 ug/ml trafficking inhibitor brefeldin A | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 7. | ALA1786685 | F | Antagonist activity at TRPV1 channel in C57B1 mouse dorsal root ganglion cells assessed as inhibition of capsaicin-induced calcium flux at 125 uM after 3 hrs by fluorometric analysis in presence of 6.3 ug/ml transcriptional inhibitor actinomycin D | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 8. | ALA2167885 | B | Displacement of [3H]RTX from TRPV1 receptor in mouse brain fraction | Mus musculus | 4 | tissue-based format | Scientific Literature | ||
| 9. | ALA2328385 | B | Displacement of [3H]resiniferatoxin from TRPV1 in mouse cortical slices | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3791380 | B | Antagonist activity at mouse TRPV1 stably expressed in human SH-SY5Y cells assessed as inhibition of capsaicin mediated calcium flux at 50 uM preincubated for 60 mins followed by capsaicin addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3791381 | B | Antagonist activity at mouse TRPV1 stably expressed in human SH-SY5Y cells assessed as inhibition of capsaicin mediated calcium flux at 0.5 to 50 uM preincubated for 60 mins followed by capsaicin addition by Fluo-4 NW dye based fluorometric assay in presence of ruthenium dye | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4001633 | B | Agonist activity at recombinant mouse TRPV1 expressed in HEK293 cells assessed as increase in calcium influx at 10 uM measured for 380 sec by Fluo-4 dye based FLIPR assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4001634 | B | Agonist activity at recombinant mouse TRPV1 expressed in HEK293 cells assessed as increase in calcium influx at 0.01 to 1 uM measured for 380 sec by Fluo-4 dye based FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4001635 | B | Agonist activity at recombinant mouse TRPV1 expressed in HEK293 cells assessed as increase in calcium influx up to 10 uM measured for 380 sec by Fluo-4 dye based FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4158688 | B | Antagonist activity at TRPV1 in C57/BL6 mouse cerebellar granule cells assessed as inhibition of KCl-induced voltage dependent calcium entry at 10 uM by fura-2-based assay | Mus musculus | 7 | assay format | Scientific Literature | ||
| 16. | ALA4256798 | B | Antagonist activity at mouse TRPV1 expressed in human SH-SY5Y cells assessed as inhibition of capsaicin induced calcium influx at 0.001 to 100 uM incubated for for 60 mins by Fluo-4 NW-dye based fluorimetric assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4260169 | B | Antagonist activity at TRPV1 channel in mouse DRG neurons assessed as inhibition of capsaicin-induced calcium accumulation at 300 uM incubated for 6 mins by Fura-2-AM dye based fluorescence assay relative to control | Mus musculus | 7 | single protein format | Scientific Literature | ||
| 18. | ALA4423721 | B | Antagonist activity at mouse TRPV1 expressed in HEK293T cells assessed as inhibition of 2-APB evoked currents at 3 to 10 uM -60 mV holding potential by whole-cell patch clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4423729 | B | Antagonist activity at mouse TRPV1 S513F/T55IL double mutant expressed in HEK293T cells assessed as inhibition of 2-APB evoked currents at 0.3 to 10 uM at -60 mV holding potential by whole-cell patch clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4423730 | B | Antagonist activity at mouse TRPV1 S513F mutant expressed in HEK293T cells assessed as inhibition of 2-APB evoked currents at 0.3 to 10 uM at -60 mV holding potential by whole-cell patch clamp assay | Mus musculus | 1 | cell-based format | Scientific Literature |
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