# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1786486 | B | Binding affinity to histidine-tagged Grp78 by surface plasmon resonance analysis | 14 | single protein format | Scientific Literature | |||
2. | ALA1786489 | B | Binding affinity to Grp78 by isothermal titration calorimetric analysis | 6 | single protein format | Scientific Literature | |||
3. | ALA1794423 | F | PUBCHEM_BIOASSAY: Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in human glioma: Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504849] | 31 | assay format | PubChem BioAssays | |||
4. | ALA1963893 | F | PUBCHEM_BIOASSAY: qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS. (Class of assay: confirmatory) | 3,181 | assay format | PubChem BioAssays | |||
5. | ALA3578650 | B | Inhibition of 2-deoxyglucose-induced GRP78 (unknown origin) expression transfected in human HT1080 cells by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3768686 | B | Induction of glucose-regulated protein 78 in HEK293 cells at 200 uM after 6 hrs by Western blotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4270821 | B | Binding affinity to 78 kDa glucose-regulated protein in human Hela cells lysates assessed as protein enrichment by measuring normalized heavy/light ratio at by nano-LC-ESIMS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4388991 | B | Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG fluorescent peptide addition in presence of 20 uM ADP followed by further incubation for 2 hrs by fluorescence polarization assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
9. | ALA4388992 | B | Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG fluorescent peptide addition in presence of 10 uM ADP followed by further incubation for 2 hrs by fluorescence polarization assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4388993 | B | Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG fluorescent peptide addition in presence of 100 uM ADP followed by further incubation for 2 hrs by fluorescence polarization assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4388997 | B | Inhibition of GRP78 in human HCT116 cells assessed as increase in unfolded protein response marker XBP1 level measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4388998 | B | Inhibition of GRP78 in human HCT116 cells assessed as increase in unfolded protein response marker ATF4 level measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4388999 | B | Inhibition of GRP78 in human HCT116 cells assessed as increase in unfolded protein response marker CHOP level measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4389007 | B | Inhibition of recombinant GRP78 substrate binding domain ( 419 to 633 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG fluorescent peptide addition in presence of 20 uM ADP followed by further incubation for 2 hrs by fluorescence polarization assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA4686292 | B | Binding affinity to human GRP78 at 1 uM measured after 30 mins by UF-ASMS analysis relative to control | Homo sapiens | 14 | single protein format | Scientific Literature | ||
16. | ALA4686299 | B | Binding affinity to N-terminal His-tagged GRP78 (unknown origin) assessed as change in melting temperature at 500 uM by differential scanning fluorimetry | Homo sapiens | 5 | single protein format | Scientific Literature | ||
17. | ALA4713548 | B | Binding affinity to 78 kDa glucose-regulated protein in human A549 cells by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |