# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1787264 | B | Inhibition of TPA-induced degradation of Pdcd4 (amino acid 39-91) expressed in human HEK293 cells assessed as minimum compound concentration required for 50% recovery of Pdcd4-luciferase signal incubated for 8 hrs by luciferase reporter gene assay | 9 | ALA1782046 | cell-based format | Scientific Literature | ||
2. | ALA1913571 | B | Stabilization of Pdcd4 expressed in human HEK293 cells assessed as inhibition of TPA-induced degradation by luciferase reporter assay | Homo sapiens | 4 | ALA1909608 | cell-based format | Scientific Literature | |
3. | ALA1913572 | B | Stabilization of Pdcd4 expressed in TPA-stimulated human HEK293 cells at 2.5 uM by luciferase reporter assay | Homo sapiens | 1 | ALA1909608 | cell-based format | Scientific Literature | |
4. | ALA3295252 | B | Inhibition of TPA-induced PDCD4 degradation in human MCF7 cells at 1 uM treated 30 mins before TPA challenge measured after 6 hrs by Western blot analysis relative to TPA treated control | Homo sapiens | 7 | ALA3286090 | cell-based format | Scientific Literature | |
5. | ALA3295259 | B | Inhibition of TPA-induced PDCD4 degradation in human MCF7 cells at 10 nM treated 30 mins before TPA challenge measured after 6 hrs by Western blot analysis relative to TPA treated control | Homo sapiens | 1 | ALA3286090 | cell-based format | Scientific Literature | |
6. | ALA5140522 | B | Inhibition of PDCD4 in human HeLa cells tranfected with pCI-neo-luciferase-PDCD4 3'-UTR plasmid assessed as increase in luciferase activity by luciferase reporter assay | Homo sapiens | 1 | ALA5137049 | cell-based format | Scientific Literature | |
7. | ALA5140628 | B | Inhibition of PDCD4 in human HeLa cells tranfected with pCI-neo-luciferase-PDCD4 3'-UTR plasmid assessed as fold change in luciferase signal by measuring relative luciferase unit by luciferase reporter assay | Homo sapiens | 37 | ALA5137049 | cell-based format | Scientific Literature |