# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1794499 | F | PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] | 13,676 | assay format | PubChem BioAssays | |||
2. | ALA1920074 | B | Inhibition of RGS4 GTPase accelrating activity | 1 | single protein format | Scientific Literature | |||
3. | ALA1963917 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Regulator of G Protein Signaling(RGS) 4: Hit Validation. (Class of assay: confirmatory) | 25 | assay format | PubChem BioAssays | |||
4. | ALA2039222 | B | Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay | 41 | single protein format | Scientific Literature | |||
5. | ALA2114763 | F | PubChem BioAssay. Counter screen dose-response assay for SAR compounds that potentiate the regulator of G-protein signaling 4 (RGS4) in non-induced RGS4 cells. (Class of assay: confirmatory) | Homo sapiens | 9 | cell-based format | PubChem BioAssays | ||
6. | ALA3706279 | B | Inhibitory Assay: FCPIA Characterization of RGS Inhibitory Activity: CCG-50014 (FIG. 1) was originally identified as a potential inhibitor of RGS8 and RGS16 in a polyplex high throughput screen to identify inhibitors of the RGS-Gα interaction [4]. This activity was confirmed by analyzing the effect of CCG-50014 on several different RGS proteins with freshly reordered compound using multiplexed FCPIA. CCG-50014 fully inhibited several different RGS proteins including RGS4, 8, 16, and 19, but did not have activity on RGS7 or a mutated form of RGS4 that lacks cysteine residues. | 4 | single protein format | BindingDB Database |