| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1805238 | B | Binding affinity to Fc-IgG-tagged DC-SIGN carbohydrate recognizing domain at 1 mM | 3 | single protein format | Scientific Literature | |||
| 2. | ALA2185436 | B | Displacement of biotinylated-TM PAA from human DC-SIGN at 50 mM after 3 hrs by colorimetry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2185446 | B | Displacement of biotinylated-TM PAA from human DC-SIGN at 1 mM after 3 hrs by colorimetry | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA3123558 | B | Antagonist activity at DC-SIGN receptor (unknown origin) assessed as inhibition of mannosylated BSA binding by SPR assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA3123563 | B | Antagonist activity at DC-SIGN receptor in human DC cells assessed as inhibition of cell-adhesion at 500 uM by CFSE fluorescence assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 6. | ALA3123564 | B | Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive displacement assay | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 7. | ALA3123565 | B | Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA3134882 | B | Binding affinity to DC-SIGN (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 9. | ALA3598580 | B | Antagonist activity at DC-SIGN-CRD (unknown origin) by competitive binding assay | Homo sapiens | 19 | single protein format | Scientific Literature | ||
| 10. | ALA4043671 | B | Inhibition of binding of immobilized mannosylated BSA to DC-SIGN extracellular domain (66 to 404 residues) (unknown origin) expressed in Escherichia coli by SPR assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA4264749 | B | Inhibition of DC-SIGN (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA4264751 | B | Inhibition of DC-SIGN (unknown origin) after 1 hr by fluorescence analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4269396 | B | Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN carbohydrate binding domain (unknown origin) expressed in Escherichia coli preincubated for 1 hr followed by TMB substrate addition measured after 30 mins by ELISA | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 14. | ALA4269397 | B | Inhibition of binding of trimannoside containing horseradish peroxidase to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli preincubated for 1 hr followed by TMB substrate addition measured after 5 mins by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4269398 | B | Binding affinity to DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli after 1 hr by ELISA | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 16. | ALA4269400 | B | Binding affinity to recombinant human DC-SIGN expressed in human Raji cells preincubated with Cy5 conjugated compound for 2 hrs followed by washing and measured by flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4269401 | B | Binding affinity to recombinant human DC-SIGN expressed in rat-6 fibroblast preincubated with Cy5 conjugated compound for 2 hrs followed by washing and measured by flow cytometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 18. | ALA4369793 | B | Binding affinity to human DC-SIGN ECD expressed in Escherichia coli BL21(DE3) after 1 hr by Man-Fl-BSA assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 19. | ALA4376907 | B | Binding affinity to human DC-SIGN by SPR analysis | Homo sapiens | 3 | single protein format | Scientific Literature |
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