| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1810435 | B | Inhibition of recombinant catalytic domain of TMPRSS2 expressed in Escherichia coli using Dcyclohexylalanine- Pro-Arg-AMC as substrate by fluorescence plate reader analysis | 3 | ALA1806464 | assay format | Scientific Literature | ||
| 2. | ALA4709149 | B | Induction of downregulation of TMPRSS2 (unknown orgin) human LNCaP cells at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706528 | tissue-based format | Scientific Literature | |
| 3. | ALA4709152 | B | Induction of downregulation of TMPRSS2 (unknown orgin) human LNCaP cells at 2 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706528 | tissue-based format | Scientific Literature | |
| 4. | ALA4709155 | B | Induction of downregulation of TMPRSS2 (unknown orgin) human LNCaP cells at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4706528 | tissue-based format | Scientific Literature | |
| 5. | ALA4723156 | B | Inhibition of human TMPRSS2-mediated SARS-CoV-2 entry into human Caco-2 cells | Homo sapiens | 1 | ALA4715853 | cell-based format | Scientific Literature | |
| 6. | ALA5134044 | B | Binding affinity to TMPRSS2 (unknown origin) at 1.875 to 50 uM by SPR assay | Homo sapiens | 2 | ALA5131463 | single protein format | Scientific Literature | |
| 7. | ALA5155356 | B | Inhibition of recombinant human TMPRSS2 assessed as remaining activity at 50 uM using Boc-QAR-AMC as substrate preincubated for 15 mins followed by substrate addition by fluorometric assay | Homo sapiens | 1 | ALA5154645 | single protein format | Scientific Literature | |
| 8. | ALA5216080 | B | Inhibition of TMPRSS2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using H-D cyclohexylalanine-Pro-Arg-AM as substrate by Dixon method | Homo sapiens | 6 | ALA5214916 | assay format | Scientific Literature | |
| 9. | ALA5252274 | B | Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed by substrate addition measured after 30 mins by fluorescence based microscopic analysis | Homo sapiens | 3 | ALA5247670 | assay format | Scientific Literature | |
| 10. | ALA5252279 | B | Inhibition of TMPRSS2 (106 to 492 residues) (unknown origin) using Boc-QAR-AMC as substrate measured for 20 mins by spectrophotometer analysis | Homo sapiens | 9 | ALA5247670 | single protein format | Scientific Literature |
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