| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1817387 | B | Inhibition of Fragile histidine triad protein hydrolytic activity | 5 | ALA1811807 | single protein format | Scientific Literature | ||
| 2. | ALA3860849 | A | Stability of compound assessed as human Fhit expressed in Escherichia coli BL21-mediated compound initial rate of hydrolysis per microgram of protein at 50 to 200 uM after 5 to 120 mins by RP-HPLC analysis | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 3. | ALA3860850 | A | Stability of the compound assessed as human Fhit expressed in Escherichia coli BL21-mediated compound hydrolysis rate per microgram protein at 50 uM after 5 to 120 mins by RP-HPLC analysis | Homo sapiens | 7 | ALA3860051 | assay format | Scientific Literature | |
| 4. | ALA3860864 | B | Activity at human Fhit expressed in Escherichia coli BL21 assessed as enzyme Km by Michaelis-Menten equation | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 5. | ALA3860865 | B | Activity at human Fhit expressed in Escherichia coli BL21 assessed as enzyme Kcat by Michaelis-Menten equation | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 6. | ALA3860866 | B | Activity at human Fhit expressed in Escherichia coli BL21 assessed as ratio of enzyme Kcat to Km by Michaelis-Menten equation | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 7. | ALA3860867 | B | Activity at human Fhit expressed in Escherichia coli SG100 assessed as enzyme Kcat by Michaelis-Menten equation | Homo sapiens | 1 | ALA3860051 | assay format | Scientific Literature | |
| 8. | ALA3860868 | B | Activity at human Fhit expressed in Escherichia coli SG100 assessed as ratio of enzyme Kcat to Km by Michaelis-Menten equation | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 9. | ALA3860869 | B | Activity at human Fhit expressed in Escherichia coli SG100 assessed as enzyme Km by Michaelis-Menten equation | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 10. | ALA3860870 | B | Activity at human Fhit expressed in Escherichia coli BL 21 assessed as enzyme Km by Michaelis-Menten equation relative to control | Homo sapiens | 3 | ALA3860051 | assay format | Scientific Literature | |
| 11. | ALA3860872 | B | Activity at human Fhit expressed in Escherichia coli SG100 assessed as enzyme Vmax by Michaelis-Menten equation | Homo sapiens | 2 | ALA3860051 | assay format | Scientific Literature | |
| 12. | ALA5033267 | B | Inhibition of recombinant human FHIT incubated for 1hr in presence of tokyogreen-labeled CMP probe by fluorescence based analysis | Homo sapiens | 22 | ALA5032508 | single protein format | Scientific Literature | |
| 13. | ALA5033272 | B | Inhibition of recombinant human FHIT assessed as reduction in AP3Aase activity measured after 45 mins by HPLC analysis | Homo sapiens | 13 | ALA5032508 | single protein format | Scientific Literature | |
| 14. | ALA5033273 | B | Inhibition of recombinant human FHIT at 10 uM incubated for 1 hr by fluorescence based analysis relative to control | Homo sapiens | 8 | ALA5032508 | single protein format | Scientific Literature | |
| 15. | ALA5033274 | B | Inhibition of recombinant human FHIT assessed as reduction in AP3Aase activity at 50 uM measured after 45 mins by HPLC analysis relative to control | Homo sapiens | 4 | ALA5032508 | single protein format | Scientific Literature | |
| 16. | ALA5033277 | B | Substrate activity at human recombinant FHIT assessed as Km by Michaelis-Menten analysis | Homo sapiens | 1 | ALA5032508 | single protein format | Scientific Literature | |
| 17. | ALA5033278 | B | Substrate activity at human recombinant FHIT assessed as Kcat by Michaelis-Menten analysis | Homo sapiens | 1 | ALA5032508 | single protein format | Scientific Literature | |
| 18. | ALA5033280 | B | Noncompetitive inhibition of human recombinant FHIT assessed as reduction in hydrolysis of TG-CMP at 1 to 9 uM measured for 30 mins by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA5032508 | single protein format | Scientific Literature | |
| 19. | ALA5033284 | B | Substrate activity at human recombinant FHIT assessed as Kcat/Km by Michaelis-Menten analysis | Homo sapiens | 4 | ALA5032508 | single protein format | Scientific Literature | |
| 20. | ALA5033286 | B | Inhibition of human FHIT expressed in Escherichia coli BL21(DE3)-RIL cells using AP3A as substrate pretreated for 10 mins followed by substrate addition and measured after 1 hr by HPLC analysis | Homo sapiens | 1 | ALA5032508 | cell-based format | Scientific Literature |
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