| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA872293 | B | Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH | 6 | cell-based format | Scientific Literature | |||
| 2. | ALA883662 | B | Inhibitory constant against thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells upon incubation at 37 degree C for 1 hr at pH 7.4 using [3H]Ntau(1)-Me-His-TRH; Range = 0.12-0.24 uM | 1 | cell-based format | Scientific Literature | |||
| 3. | ALA884982 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8 | 2 | cell-based format | Scientific Literature | |||
| 4. | ALA885038 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.21-5.7 uM | 1 | cell-based format | Scientific Literature | |||
| 5. | ALA885039 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 h at 37 degree C and pH 7.8; Range = 0.69-3.2 uM | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA885040 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.76-2.2 uM | 1 | cell-based format | Scientific Literature | |||
| 7. | ALA872070 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.19-0.85 uM | 1 | cell-based format | Scientific Literature | |||
| 8. | ALA872190 | B | Signaling (activation) potency for thyrotropin releasing hormone receptor 2 expressed in HEK 293EM cells with CREB-luciferase reporter upon incubation with the compound for 6 hr at 37 degree C and pH 7.8; Range = 0.011-0.052 uM | 1 | cell-based format | Scientific Literature | |||
| 9. | ALA917827 | B | Displacement of [3H]N(1)-Me-His-TRH from TRHR2 | 17 | single protein format | Scientific Literature | |||
| 10. | ALA917829 | F | Agonist activity at TRHR2 expressed in HEK293EM cells assessed as activation potency by measuring CREB-luciferase reporter activity | 17 | cell-based format | Scientific Literature | |||
| 11. | ALA973227 | B | Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRHR2 expressed in HEK2935 cells | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA973283 | B | Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRH2 receptor expressed in HEK2935 cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA973284 | B | Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRH2 receptor expressed in HEK2935 cells up to 1 mM | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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