| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1837097 | B | Induction of current in human PCFT expressed in xenopus oocyte at 5 uM at holding potential -90 mV by voltage clamp assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 2. | ALA1837098 | B | Inhibition of human PCFT-mediated [3H]MTX uptake ectopically expressed in chinese hamster R2 cells at 10 uM at pH 5.5 to 7.2 | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA1837099 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 5.5 by dixon plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1837100 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 6.8 by dixon plot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1837101 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 5.5 by dixon plot analysis relative to PMX | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA1837102 | B | Inhibition of human PCFT-mediated [3H]MTX uptake expressed in chinese hamster R2 cells at pH 6.8 by dixon plot analysis relative to PMX | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2161356 | B | Inhibition of [3H]MTX transport at human PCFT expressed in Chinese hamster R2 cells at pH 5.5 by Dixon plot | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA2161357 | B | Inhibition of [3H]MTX transport at human PCFT expressed in Chinese hamster R2 cells at pH 6.8 by Dixon plot | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA2161358 | B | Ratio of Ki for human PCFT at pH 6.8 to Ki for human PCFT at pH 5.5 by [3H]MTX transport assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA1067646 | B | Displacement of [3H]MTX from human PCFT expressed in Chinese hamster R2 cells at pH 6.8 by Dixon plot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA1067647 | B | Displacement of [3H]MTX from human PCFT expressed in Chinese hamster R2 cells at pH 5.5 by Dixon plot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA3387475 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-blue cell viability assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 13. | ALA3381410 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in PCFT-mediated [3H]MTX transport at 10 uM at pH 5.5 and 37 degC incubated for 5 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA3381411 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in PCFT-mediated [3H]MTX transport at 10 uM at pH 6.8 and 37 degC incubated for 5 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3381412 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in PCFT-mediated [3H]MTX transport at 1 uM at pH 5.5 and 37 degC incubated for 5 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA3381413 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in PCFT-mediated [3H]MTX transport at 1 uM at pH 6.8 and 37 degC incubated for 5 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3382016 | B | Inhibition of PCFT (unknown origin) expressed in Chinese hamster R2/PCFT4 cells assessed as reduction in PCFT-mediated [3H]MTX transport at pH 5.5 and 37 degC incubated for 5 mins | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA3412692 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 19. | ALA3632256 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA3632263 | B | Binding affinity to human PCFT expressed in Chinese hamster R2/PCFT4 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assay in presence of 200 nM folic acid | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!