| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1837980 | B | Inhibition of human PIP5K2alpha in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA1942472 | B | Inhibition of human PIP4K2A in HL-60 cells lysate assessed as reduction of labeling of acyl-phosphate ATP probe at 100 nM | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA2354223 | F | PubChem BioAssay. qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). (Class of assay: confirmatory) | ⋯ | assay format | PubChem BioAssays | |||
| 4. | ALA3130918 | B | Inhibition of human PIP4K2alpha assessed as residual activity at 1 uM relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA3215031 | F | PubChem BioAssay. qHTS for Inhibitors of PI5P4K: Confirmation in Primary Assay. (Class of assay: confirmatory) | 793 | assay format | PubChem BioAssays | |||
| 6. | ALA3777506 | B | Inhibition of N-terminal His6-tagged recombinant human PIP4K2A expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA3991826 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 198 | subcellular format | Kuster lab chemical proteomics drug profiling | ||
| 8. | ALA4015082 | B | Inhibition of human PI4K2alpha (1 to 479 residues) by ADP Glo HTS assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4015085 | B | Inhibition of human PIP5K2alpha (1 to 406 residues) by ADP Glo HTS assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4034459 | B | Inhibition of PIP4K2A ATP binding site (unknown origin) at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4035992 | B | Inhibition of human PIP5K2alpha (1 to 406 residues) by ADP Glo HTS assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4035994 | B | Inhibition of human PI4K2alpha (1 to 479 residues) by ADP Glo HTS assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4045802 | B | Inhibition of PIP4K2A ATP binding site (AKELPTLKDNDFINEGQK) in human PBMC at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4046043 | B | Inhibition of PIP4K2A ATP binding site (AKELPTLKDNDFINEGQK) in human PBMC at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4118452 | B | Inhibition of PIP4K2A in human SKCO1 cells at 1 uM after 4 hrs using biotin labeled AKELPTLKDNDFINEGQK probe by mass-spectrometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4181237 | B | Inhibition of recombinant human full length N-terminal His6-tagged PIP4K2alpha expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4191129 | B | Inhibition of recombinant full-length human PIP4K2alpha at 1 uM using phosphatidylinositol 5-phosphate/phosphatidylserine as substrate after 40 mins in presence of [gamma-33P]ATP by scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4266611 | B | Inhibition of recombinant human N-terminal His6-tagged PIP4K2alpha expressed in baculovirus infected Sf21 insect cells at 1 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4314983 | B | Inhibition of recombinant full-length human PIP4K2alpha assessed as residual activity at 10 uM using phosphatidylinositol 5-phosphate as substrate measured after 40 mins by HTRF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4335362 | B | Inhibition of recombinant full-length human PIP4K2alpha at 1 uM assessed as residual activity at 1 uM using phosphatidylinositol 5-phosphate as substrate measured after 40 mins by HTRF assay | Homo sapiens | 2 | single protein format | Scientific Literature |
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