| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1838138 | B | Inhibition of human Wnk4 in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA2424218 | B | Inhibition of Wnk4 in human PC3 cell lysates at 10 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 3. | ALA4025441 | B | Inhibition of wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA4034548 | B | Inhibition of Wnk4 (unknown origin) labeling at activation loop at 10 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4044252 | B | Inhibition of wild-type human partial length WNK4 (A31 to D461 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4045865 | B | Inhibition of Wnk4 activation Loop (IGDLGLATLKR) in human PBMC at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4046106 | B | Inhibition of Wnk4 activation Loop (IGDLGLATLKR) in human PBMC at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4157331 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4186110 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4231010 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4264599 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4314966 | B | Inhibition of human WNK4 using myelin basic protein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4335344 | B | Inhibition of human WNK4 assessed as residual activity at 1 uM using myelin basic protein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4337168 | B | Inhibition of recombinant human WNK4 (A31 to D461 residues) assessed as residual activity at 10 uM using myelin basic protein as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4352116 | B | Inhibition of human WNK4 using myelin basic protein as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4358188 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4382819 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4389538 | B | Inhibition of wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4390015 | B | Inhibition of wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4391641 | B | Binding affinity to wild-type human partial length WNK4 (A31 to D461 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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