| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1838363 | B | Inhibition of human RIPK3 in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA1221007 | B | Inhibition of human RIP3 autophosphorylation expressed in HEK293T cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2214442 | B | Inhibition of RIPK3 | 1 | single protein format | Scientific Literature | |||
| 4. | ALA3631113 | B | Inhibition of RIPK3 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA3736773 | B | Inhibition of full length human GST-tagged RIPK3 expressed in Spodoptera frugiperda Sf9 cells after 30 mins by scintillation and luminescence counting method in the presence of [gamma-33P]ATP | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 6. | ALA3750028 | B | Inhibition of human RIPK3 using MBP substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3825649 | B | Inhibition of RIPK3 (unknown origin) preincubated for 10 mins followed by addition of fluorescent-labeled 2-Methyl-5-(2-propen-l-yloxy)aniline measured after 10 mins by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3825650 | B | Inhibition of RIPK3 (unknown origin) in HEK-293 cells assessed as necroptic cell death at 10 uM by cell-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3991869 | B | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 243 | subcellular format | Kuster lab chemical proteomics drug profiling | ||
| 10. | ALA3993110 | B | Inhibition of full length recombinant human N-terminal GST-tagged RIP3 expressed in baculovirus infected sf9 cells at 1 uM using MBP as substrate preincubated for 15 mins followed by MBP/ATP mixture addition measured after 90 mins by ADP-Glo kinase assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3993123 | B | Inhibition of TNFalpha/z-VAD-FMK-induced RIP3 phosphorylation at Ser-227 residue in human HT-29 cells by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4001361 | B | Inhibition of human RIPK3 | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA4024000 | B | Inhibition of human RIPK3 at 10 uM using myelin basic protein as substrate in presence of [gamma33P]ATP relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4045817 | B | Inhibition of RIPK3 conserved Lys2 (DLKPSNVLLDPELHVK) in human PBMC at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4046058 | B | Inhibition of RIPK3 conserved Lys2 (DLKPSNVLLDPELHVK) in human PBMC at 0.1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4118463 | B | Inhibition of RIPK3 in human SKCO1 cells at 1 uM after 4 hrs using biotin labeled DLKPSNVLLDPELHVK probe by mass-spectrometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4119257 | B | Inhibition of human RIPK3 assessed as residual activity at 16 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4234039 | B | Inhibition of recombinant full length human RIPK3 expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-33P]ATP | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 19. | ALA4234049 | B | Inhibition of recombinant full length human RIPK3 expressed in baculovirus infected Sf9 insect cells assessed as residual activity at 10 uM using MBP as substrate in presence of [gamma-33P]ATP | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 20. | ALA4261376 | B | Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system by Kinomescan method | Homo sapiens | 1 | assay format | Scientific Literature |
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