# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA751478 | F | The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functional potency | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA751479 | F | The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functional potency; IA=inactive | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA750057 | B | Potency to displace [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 immuno-isolated from M10 cells | Gallus gallus | 22 | cell-based format | Scientific Literature | ||
4. | ALA755452 | F | Receptor activation after 10 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | assay format | Scientific Literature | |||
5. | ALA754716 | F | Receptor activation after 100 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | assay format | Scientific Literature | |||
6. | ALA754717 | F | Recovery following a 5 min wash after 10 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | assay format | Scientific Literature | |||
7. | ALA754718 | F | Recovery following a 5 min wash after 100 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | assay format | Scientific Literature | |||
8. | ALA754719 | B | Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha4-beta2 | 8 | protein complex format | Scientific Literature | |||
9. | ALA754720 | B | Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha4-beta2; low efficacy | 2 | protein complex format | Scientific Literature | |||
10. | ALA754721 | B | Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2 | 2 | protein complex format | Scientific Literature | |||
11. | ALA754722 | B | Binding affinity against human Nicotinic acetylcholine receptor alpha4-beta2 | 1 | protein complex format | Scientific Literature | |||
12. | ALA755318 | B | Compound was evaluated for its ability to displace [3H]cytisine from K177 cells expressing human Nicotinic acetylcholine receptor alpha4-beta2 | 2 | cell-based format | Scientific Literature | |||
13. | ALA755319 | F | Activation of the high- and low affinity components evoked by 3 mM ACh in the HEK293 cells stably expressing Nicotinic acetylcholine receptor alpha4-beta2 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA755320 | B | Activation responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
15. | ALA755321 | B | Activation responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes at 300 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA755322 | F | Compound was evaluated for agonist activity against activated human recombinant aNicotinic acetylcholine receptor alpha4-beta2 in Xenopus Oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA755323 | B | Responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes up to 1 mM | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA755324 | F | Compound was evaluated for agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha4-beta2 in Xenopus Oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA755325 | F | Antagonism of ACh response at Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
20. | ALA755326 | B | Binding affinity to alpha4 beta-2 receptor subtype from mouse fibroblast M10 cells was measured using [3 H]nicotine | Mus musculus | 2 | cell-based format | Scientific Literature |