| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA751478 | F | The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functional potency | Homo sapiens | 3 | ALA1129686 | assay format | Scientific Literature | |
| 2. | ALA751479 | F | The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functional potency; IA=inactive | Homo sapiens | 1 | ALA1129686 | assay format | Scientific Literature | |
| 3. | ALA750057 | B | Potency to displace [3H]nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 immuno-isolated from M10 cells | Gallus gallus | 22 | ALA1135484 | cell-based format | Scientific Literature | |
| 4. | ALA755452 | F | Receptor activation after 10 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1134328 | assay format | Scientific Literature | ||
| 5. | ALA754716 | F | Receptor activation after 100 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1134328 | assay format | Scientific Literature | ||
| 6. | ALA754717 | F | Recovery following a 5 min wash after 10 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1134328 | assay format | Scientific Literature | ||
| 7. | ALA754718 | F | Recovery following a 5 min wash after 100 uM application and 30 uM of ACh for nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1134328 | assay format | Scientific Literature | ||
| 8. | ALA754719 | B | Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha4-beta2 | 8 | ALA1130264 | protein complex format | Scientific Literature | ||
| 9. | ALA754720 | B | Compound was evaluated for functional potencies and efficacies at human Nicotinic acetylcholine receptor alpha4-beta2; low efficacy | 2 | ALA1130264 | protein complex format | Scientific Literature | ||
| 10. | ALA754721 | B | Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1130264 | protein complex format | Scientific Literature | ||
| 11. | ALA754722 | B | Binding affinity against human Nicotinic acetylcholine receptor alpha4-beta2 | 1 | ALA1132247 | protein complex format | Scientific Literature | ||
| 12. | ALA755318 | B | Compound was evaluated for its ability to displace [3H]cytisine from K177 cells expressing human Nicotinic acetylcholine receptor alpha4-beta2 | 2 | ALA1131463 | cell-based format | Scientific Literature | ||
| 13. | ALA755319 | F | Activation of the high- and low affinity components evoked by 3 mM ACh in the HEK293 cells stably expressing Nicotinic acetylcholine receptor alpha4-beta2 | Homo sapiens | 1 | ALA1147513 | cell-based format | Scientific Literature | |
| 14. | ALA755320 | B | Activation responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 | Homo sapiens | 1 | ALA1147510 | protein complex format | Scientific Literature | |
| 15. | ALA755321 | B | Activation responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes at 300 uM | Homo sapiens | 1 | ALA1147510 | cell-based format | Scientific Literature | |
| 16. | ALA755322 | F | Compound was evaluated for agonist activity against activated human recombinant aNicotinic acetylcholine receptor alpha4-beta2 in Xenopus Oocytes | Homo sapiens | 1 | ALA1130929 | cell-based format | Scientific Literature | |
| 17. | ALA755323 | B | Responses to that evoked by ACh at human Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes up to 1 mM | Homo sapiens | 2 | ALA1147510 | cell-based format | Scientific Literature | |
| 18. | ALA755324 | F | Compound was evaluated for agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha4-beta2 in Xenopus Oocytes | Homo sapiens | 1 | ALA1130929 | cell-based format | Scientific Literature | |
| 19. | ALA755325 | F | Antagonism of ACh response at Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes | Homo sapiens | 3 | ALA1147510 | cell-based format | Scientific Literature | |
| 20. | ALA755326 | B | Binding affinity to alpha4 beta-2 receptor subtype from mouse fibroblast M10 cells was measured using [3 H]nicotine | Mus musculus | 2 | ALA1136565 | cell-based format | Scientific Literature |
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