# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA751264 | F | The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functional potency | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA751873 | F | Compound was evaluated for its agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha4-beta4 in Xenopus Oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA883547 | F | Compound was evaluated for agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha4-beta4 in Xenopus Oocytes | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA750434 | B | Binding affinity against nicotinic acetylcholine receptor alpha4-beta4 using [3H]epibatidine as radioligand expressed in HEK293 cells or tsA cells | 3 | cell-based format | Scientific Literature | |||
5. | ALA830028 | B | Effective concentration against Nicotinic acetylcholine receptor alpha4-beta4 | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
6. | ALA831377 | B | Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta4; Range is 3-5 nM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
7. | ALA828423 | B | Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta4; Range is 0.3-1.5 nM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
8. | ALA828591 | B | Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta4; Range is 0.3-1.5 nM | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
9. | ALA826916 | B | Maximal response against Nicotinic acetylcholine receptor alpha4-beta4 | 13 | protein complex format | Scientific Literature | |||
10. | ALA832193 | B | Inhibitory concentration against Nicotinic acetylcholine receptor alpha4-beta4 | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
11. | ALA832194 | B | Ki or IC50 concentration against Nicotinic acetylcholine receptor alpha4-beta4 | Homo sapiens | 5 | protein complex format | Scientific Literature | ||
12. | ALA830546 | B | Ki or IC50 concentration against Nicotinic acetylcholine receptor alpha4-beta4 expressed in xenopus oocytes | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA1815450 | F | Antagonist activity against human alpha4beta4 nAChR in SHEP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ efflux | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
14. | ALA1815461 | F | Agonist activity against human alpha4beta4 nAChR in SHEP1 cells assessed as 86Rb+ efflux at 5 nM to 100 uM | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
15. | ALA931266 | B | Activation of rat nAChR alpha-3-beta-4 expressed in Xenopus oocytes assessed as modulation of nicotine-induced current by measuring ratio of I/Imax current by two-electrode voltage-clamp method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA1954612 | F | Agonist activity at alpha4beta4 nAChR receptor by FLIPR assay | 1 | assay format | Scientific Literature | |||
17. | ALA1020768 | B | Displacement of [3H]epibatidine from alpha4beta4 nAChR expressed in HEK293 cells | 21 | cell-based format | Scientific Literature | |||
18. | ALA1068091 | F | Antagonist activity at human alpha4beta4 nAChR receptor expressed in human SH-SY5Y cells assessed as inhibition of carbamylcholine-induced 86Rb+ efflux by liquid scintillation counting | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
19. | ALA1068096 | B | Intrinsic activity at human alpha4beta4 nAChR receptor expressed in human SH-SY5Y cells assessed as 86Rb+ efflux at 5 to 100 uM by liquid scintillation counting | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
20. | ALA1176284 | F | Agonist activity at alpha4beta4 nicotinic receptor in human SH-EP1 cells assessed as induction of radiolabeled Rb+ influx at 0.005 to 100 uM by liquid scintillation counting | Homo sapiens | 23 | cell-based format | Scientific Literature |