# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3424811 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR transfected in HEK293 cells by liquid scintillation counting | Rattus norvegicus | 36 | ALA3421605 | cell-based format | Scientific Literature | |
2. | ALA3579465 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR transfected in HEK293 cell membrane | Rattus norvegicus | 5 | ALA3576860 | cell-based format | Scientific Literature | |
3. | ALA3579851 | Binding | Agonist activity at rat alpha3beta4 nAChR expressed in HEK293T cells by FLIPR assay | Rattus norvegicus | 1 | ALA3576860 | cell-based format | Scientific Literature | |
4. | ALA3610679 | Binding | Agonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as mean current response at 100 uM by two-electrode voltage clamp electrophysiology assay relative to acetylcholine | Rattus norvegicus | 13 | ALA3608275 | cell-based format | Scientific Literature | |
5. | ALA3610682 | Binding | Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by measuring remaining current at 100 uM by two-electrode voltage clamp electrophysiology assay relative to control | Rattus norvegicus | 13 | ALA3608275 | cell-based format | Scientific Literature | |
6. | ALA3610961 | Binding | Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced mean current response by two-electrode voltage clamp electrophysiology assay | Rattus norvegicus | 8 | ALA3608275 | cell-based format | Scientific Literature | |
7. | ALA3620132 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nACHR expressed in HEK293 cells after 4 hrs by scintillation counting assay | Rattus norvegicus | 33 | ALA3616394 | cell-based format | Scientific Literature | |
8. | ALA3620135 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nACHR expressed in HEK293 cells after 1 hr by scintillation counting assay | Rattus norvegicus | 1 | ALA3616394 | cell-based format | Scientific Literature | |
9. | ALA3620249 | Binding | Agonist activity at recombinant rat alpha3beta4 nAChR expressed in HEK293 cells at 300 uM after 30 min by FLIPR potential blue assay | Rattus norvegicus | 6 | ALA3616394 | cell-based format | Scientific Literature | |
10. | ALA3620250 | Binding | Agonist activity at recombinant rat alpha3beta4 nAChR expressed in HEK293 cells at >=100 uM after 30 min by FLIPR potential blue assay | Rattus norvegicus | 2 | ALA3616394 | cell-based format | Scientific Literature | |
11. | ALA3620251 | Binding | Antagonist activity at recombinant rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of acetylcholine-induced effect at >=100 uM after 30 min by FLIPR potential blue assay | Rattus norvegicus | 1 | ALA3616394 | cell-based format | Scientific Literature | |
12. | ALA3624575 | Binding | Displacement of [3H]epibatidine from rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cell membranes incubated for 4 hrs by scintillation counting method | Rattus norvegicus | 19 | ALA3621161 | cell-based format | Scientific Literature | |
13. | ALA3624578 | Binding | Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 300 uM by FMP assay | Rattus norvegicus | 2 | ALA3621161 | cell-based format | Scientific Literature | |
14. | ALA3624579 | Binding | Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assay | Rattus norvegicus | 4 | ALA3621161 | cell-based format | Scientific Literature | |
15. | ALA3624580 | Binding | Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assay | Rattus norvegicus | 3 | ALA3621161 | cell-based format | Scientific Literature | |
16. | ALA839474 | Binding | Binding affinity for rat Nicotinic acetylcholine receptor alpha3-beta4 | Rattus norvegicus | 1 | ALA1140237 | protein complex format | Scientific Literature | |
17. | ALA838851 | Binding | Inhibition of [3H]epibatidine binding to rat Nicotinic acetylcholine receptor alpha3-beta4 | Rattus norvegicus | 11 | ALA1142717 | protein complex format | Scientific Literature | |
18. | ALA829040 | Binding | Displacement of [3H]epibatidine from Alpha3 Beta4 Nicotinic acetylcholine receptor of rat brain homogenates | Rattus norvegicus | 11 | ALA1141139 | assay format | Scientific Literature | |
19. | ALA829847 | Binding | Displacement of [3H]epibatidine from rat alpha3-beta4 nicotinic acetylcholine receptor; nd is not determined | Rattus norvegicus | 1 | ALA1141139 | protein complex format | Scientific Literature | |
20. | ALA829996 | Binding | Effective concentration against alpha3-beta4 Nicotinic acetylcholine receptor (nAChR) | Rattus norvegicus | 1 | ALA1141139 | protein complex format | Scientific Literature |