# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA857972 | B | In vitro binding affinity towards (alpha-4)2(beta-2)3 neuronal nicotinic acetylcholine receptor in P2 membrane fractions of rat forebrain | 66 | cell membrane format | Scientific Literature | |||
2. | ALA640626 | B | Binding affinity towards nicotinic receptor in rat brain using [3H]cytisine ligand | Rattus norvegicus | 1 | tissue-based format | Scientific Literature | ||
3. | ALA750484 | B | Nicotinic acetylcholine receptor binding activity was determined by ability to displace [3H]- (-) cytisine binding from whole rat brain synaptic membranes. | 27 | assay format | Scientific Literature | |||
4. | ALA872674 | B | Ability of compound to compete with 50 pM of 5-[125I]iodo-A-85,380 for receptor binding sites in rat brain membranes at room temperature | 23 | cell membrane format | Scientific Literature | |||
5. | ALA750930 | B | In vitro inhibition of 5-(125I)A-85380 binding to nicotinic acetylcholine receptor (nAChR) of rat brain | Rattus norvegicus | 11 | assay format | Scientific Literature | ||
6. | ALA755329 | B | Binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 by displacement of [3H](-)-cytisine from whole rat brain membranes | Rattus norvegicus | 11 | cell membrane format | Scientific Literature | ||
7. | ALA755330 | B | Affinity at alpha4-beta2 nACh receptors in rat brain (minus cerebellum) homogenates. | 23 | tissue-based format | Scientific Literature | |||
8. | ALA755332 | B | Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor alpha4-beta2 | 5 | protein complex format | Scientific Literature | |||
9. | ALA755333 | B | Compound was evaluated for functional potencies and efficacies at rat Nicotinic acetylcholine receptor alpha4-beta2; low efficacy | 1 | protein complex format | Scientific Literature | |||
10. | ALA755334 | B | Compound was evaluated for functional potencies and efficacies at rat Recombinant Nicotinic acetylcholine receptor alpha4-beta2; low efficacy | 1 | protein complex format | Scientific Literature | |||
11. | ALA755335 | B | Compound was evaluated for functional potencies and efficacies at ratNicotinic acetylcholine receptor alpha4-beta2 | 1 | protein complex format | Scientific Literature | |||
12. | ALA755336 | B | Compound was evaluated for functional potency and efficacy at human Nicotinic acetylcholine receptor alpha4-beta2 | 1 | protein complex format | Scientific Literature | |||
13. | ALA755476 | B | Functional potency for Nicotinic acetylcholine receptor alpha4-beta2 (rat brain) | 4 | assay format | Scientific Literature | |||
14. | ALA755477 | B | In vitro binding affinity for Nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortical membrane using [3H]cytisine as radioligand | 25 | cell membrane format | Scientific Literature | |||
15. | ALA755478 | B | Inhibition of binding of [3H]nicotine to Nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortical membranes at 100 uM concentration | 10 | cell membrane format | Scientific Literature | |||
16. | ALA755479 | B | The compound was evaluated for percentage inhibition of binding of [3H]- nicotine to Nicotinic acetylcholine receptor alpha4-beta2 in Rat Cerebral Cortical Membranes | 10 | protein complex format | Scientific Literature | |||
17. | ALA883403 | B | Tested for binding affinity against Nicotinic acetylcholine receptor alpha4-beta2 | 1 | protein complex format | Scientific Literature | |||
18. | ALA754303 | B | Displacement of [3H]cytisine from Nicotinic acetylcholine receptor alpha4-beta2 in rat forebrain | Rattus norvegicus | 9 | assay format | Scientific Literature | ||
19. | ALA754233 | B | Affinity for Nicotinic acetylcholine receptor alpha4-beta2 in rat brain | 2 | tissue-based format | Scientific Literature | |||
20. | ALA755999 | B | Binding affinity at rat brain Nicotinic acetylcholine receptor alpha4-beta2 | 9 | assay format | Scientific Literature |