# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1816618 | B | Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique | 32 | cell-based format | Scientific Literature | |||
2. | ALA1816889 | B | Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV by two-microelectrode voltage clamp technique relative to GABA | 32 | cell-based format | Scientific Literature | |||
3. | ALA1817161 | B | Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding potential -70 mV at 30 uM by two-microelectrode voltage clamp technique relative to GABA | 32 | cell-based format | Scientific Literature | |||
4. | ALA2148420 | B | Allosteric modulation of gamma-aminobutyric acid receptor A alpha1beta2 expressed in Xenopus oocytes assessed as potentiation of GABA-mediated chloride current at 30 uM by voltage clamp analysis | 2 | cell-based format | Scientific Literature | |||
5. | ALA2148421 | B | Allosteric modulation of gamma-aminobutyric acid receptor A alpha1beta2 expressed in Xenopus oocytes assessed as potentiation of GABA-mediated chloride current at 100 uM by voltage clamp analysis | 2 | cell-based format | Scientific Literature | |||
6. | ALA4192105 | B | Modulation of human alpha1beta2 GABAA receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current at 1 mM at -60 mV holding potential by two-electrode voltage clamp electrophysiology method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA4731523 | B | Positive allosteric modulator activity at human alpha1beta2S GABA-A receptor expressed in Xenopus laevis oocytes assessed as potentiation of EC50 GABA response at 40 uM by two electrode voltage-clamp assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4731524 | B | Positive allosteric modulator activity at human alpha1beta2S GABA-A receptor expressed in Xenopus laevis oocytes assessed as change in GABA EC50 at 40 uM by two electrode voltage-clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA5147915 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5147916 | B | Positive allosteric modulation of recombinant GABAA alpha1beta2 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at -70 mV holding potential in presence of GABA EC3 to 7 by two-microelectrode voltage-clamp assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |