# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3606992 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) expressed in baculovirus infected insect cells using GST-fused pRb (792 to 928) as substrate preincubated for 2 mins followed by [gamma-32P]-ATP addition measured after 15 mins by beta plate counting analysis | Homo sapiens | 1 | ALA3603804 | cell-based format | Scientific Literature | |
2. | ALA3606999 | Binding | Inhibition of human CDK4/cyclin D1 expressed in insect cells assessed as phosphorylation of CTRF after 50 mins by microplate scintillation counter | Homo sapiens | 4 | ALA3603804 | cell-based format | Scientific Literature | |
3. | ALA3607003 | Binding | Competitive inhibition of human CDK4/cyclin D1 expressed in insect cells assessed as phosphorylation of CTRF after 50 mins by Michaelis-Menten plot analysis in presence of ATP | Homo sapiens | 1 | ALA3603804 | cell-based format | Scientific Literature | |
4. | ALA3607099 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) by ELISA | Homo sapiens | 1 | ALA3603804 | protein complex format | Scientific Literature | |
5. | ALA3607102 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) expressed in baculovirus infected insect Sf9 cells assessed as inhibition of GST-tagged Rb phosphorylation after 30 mins in presence of [33P]-ATP | Homo sapiens | 3 | ALA3603804 | cell-based format | Scientific Literature | |
6. | ALA3632301 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | protein complex format | Scientific Literature | |
7. | ALA3750384 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) | Homo sapiens | 1 | ALA3745712 | protein complex format | Scientific Literature | |
8. | ALA3751549 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) at 10 uM | Homo sapiens | 9 | ALA3745672 | protein complex format | Scientific Literature | |
9. | ALA3750786 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3745672 | protein complex format | Scientific Literature | |
10. | ALA3748661 | Binding | Inhibition of human CDK4/cyclin D1 using RB-CTF as substrate | Homo sapiens | 1 | ALA3745707 | protein complex format | Scientific Literature | |
11. | ALA3767162 | Binding | Inhibition of CDK4/cyclin D1 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3763027 | protein complex format | Scientific Literature | |
12. | ALA3767307 | Binding | Inhibition of CDK4/Cyclin D1 (unknown origin) using RPPTLSPIPHIPR peptide as substrate in presence of [gamma-33P]ATP | Homo sapiens | 5 | ALA3763042 | protein complex format | Scientific Literature | |
13. | ALA3789978 | Binding | Inhibition of CDK4D1 (unknown origin) in presence of [gamma33P]ATP | Homo sapiens | 6 | ALA3785066 | protein complex format | Scientific Literature | |
14. | ALA3801088 | Binding | Inhibition of full length human recombinant N-terminal GST-tagged CDK4/Cyclin D1 expressed in baculovirus infected sf9 cells using RB-CTF as substrate at 100 uM incubated for 10 mins by scintillation counting method relative to control | Homo sapiens | 4 | ALA3797082 | cell-based format | Scientific Literature | |
15. | ALA3801106 | Binding | Inhibition of CDK4/Cyclin D1 (unknown origin) | Homo sapiens | 2 | ALA3797082 | protein complex format | Scientific Literature | |
16. | ALA3802055 | Binding | Inhibition of full length wild type human CDK4-cyclinD1 expressed in mammalian system assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3797029 | assay format | Scientific Literature | |
17. | ALA3817235 | Binding | Inhibition of human CDK4/cyclin D1 at 1 uM using RB-CTF as substrate | Homo sapiens | 1 | ALA3813650 | protein complex format | Scientific Literature | |
18. | ALA3821030 | Binding | Inhibition of recombinant human CDK4/cyclin D1 using fluoresceinyl-AhxPro-Val-Lys-Arg-Arg-Leu-(3ClPhe)-Gly as substrate incubated for 45 mins by fluorescence polarization assay | Homo sapiens | 22 | ALA3817805 | protein complex format | Scientific Literature | |
19. | ALA659122 | Binding | Inhibition of human cyclin dependent kinase 4 (CDK4/D1) at 50 uM | Homo sapiens | 2 | ALA1134251 | protein complex format | Scientific Literature | |
20. | ALA659123 | Binding | In vitro inhibitory activity against human cyclin dependent kinase (CDK4/D1) | 40 | ALA1134251 | protein complex format | Scientific Literature |