| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA747508 | B | Activity against cloned ionotropic N-methyl-D-aspartate glutamate receptor 1/2A; Not active | 1 | protein complex format | Scientific Literature | |||
| 2. | ALA750561 | B | Inhibitory activity against Xenopus laevis oocyte expressing 1A/2A heteromeric human NMDA (hNMDA) receptor | 18 | protein complex format | Scientific Literature | |||
| 3. | ALA832009 | B | Inhibitory activity against recombinant NR1/NR2A receptor expressed in cells | 14 | cell-based format | Scientific Literature | |||
| 4. | ALA871335 | B | Inhibitory activity against NR1A expressed in combination with NR2A at 15 uM | 1 | assay format | Scientific Literature | |||
| 5. | ALA909226 | F | Inhibition of NMDA-evoked current in EcR293 cells transfected with NR1/NR2A upto 10 uM by patch clamp method | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA889736 | F | Antagonist activity at recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA1805127 | F | Antagonist activity against NR1a/NR2A receptor transfected in human HEK293 cells assessed as inhibition of NMDA-induced Ca2+ influx at 10 uM | 8 | cell-based format | Scientific Literature | |||
| 8. | ALA933583 | B | Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response | 3 | cell-based format | Scientific Literature | |||
| 9. | ALA933584 | B | Activity at NR1/NR2A receptor expressed in xenopus oocytes assessed as Inhibition of L-glutamate and glycine-induced current response at 100 uM | 2 | cell-based format | Scientific Literature | |||
| 10. | ALA933585 | B | Inhibition of NR1/NR2A receptor expressed in xenopus oocytes assessed as effect on L-glutamate and glycine-induced current response | 1 | cell-based format | Scientific Literature | |||
| 11. | ALA1105653 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release after 30 mins | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
| 12. | ALA1105654 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 25 uM after 30 mins | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 13. | ALA1105657 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 100 uM after 30 mins | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA1105658 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 20 uM after 30 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1105659 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 50 nM after 30 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA1105660 | B | Inhibition of human NR1-1a/NR2A receptor-mediated excitotoxicity mouse L12-G10 cells assessed as LDH release after 30 mins in absence of (S)-glutamate/glycine relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA1105661 | B | Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assessed as LDH release at 10 uM after 30 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA1225540 | F | Antagonist activity at wild type NR1/NR2A receptor expressed in Xenopus oocytes assessed as ratio of residual current induced by agonist in presence of compound to residual current induced by agonist alone at 10 uM by two-electrode voltage-clamp method | 24 | cell-based format | Scientific Literature | |||
| 19. | ALA1225543 | F | Antagonist activity at wild type NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of agonist-induced current amplitude at 10 uM by two-electrode voltage-clamp method | 4 | cell-based format | Scientific Literature | |||
| 20. | ALA1274344 | F | Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at 0.1 uM at -60mV holding potential by two-electrode voltage-clamp electrophysiology | 3 | cell-based format | Scientific Literature |
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