# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3594878 | Binding | Inhibition of NMDA receptor in rat hippocampal neurons assessed as inhibition of glutamate-evoked current by whole-cell voltage-clamp method | Rattus norvegicus | 1 | ALA3593227 | tissue-based format | Scientific Literature | |
2. | ALA3595950 | Binding | Displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor by beta counting analysis in absence of spermine | Rattus norvegicus | 81 | ALA3593210 | assay format | Scientific Literature | |
3. | ALA3595951 | Binding | Displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor by beta counting analysis in presence of 30 uM spermine | Rattus norvegicus | 79 | ALA3593210 | assay format | Scientific Literature | |
4. | ALA3595952 | Binding | Ratio of IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in presence of 30 uM spermine to IC50 for displacement of [3H]-MK-801 from rat cortical membranes NMDA receptor in absence of 30 spermine | Rattus norvegicus | 79 | ALA3593210 | assay format | Scientific Literature | |
5. | ALA3595953 | Binding | Displacement of [3H]-ifenprodil from rat cortical membranes NMDA receptor by beta counting analysis in absence of spermine | Rattus norvegicus | 79 | ALA3593210 | assay format | Scientific Literature | |
6. | ALA3595954 | Binding | Competitive inhibition of [3H]-MK-801 binding to rat cortical membranes NMDA receptor at 3 to 100 uM by beta counting analysis in presence of spermine | Rattus norvegicus | 3 | ALA3593210 | assay format | Scientific Literature | |
7. | ALA3619813 | Binding | Displacement of [3H]MK-801 from NMDA receptor in Wistar rat brain membranes by scintillation counting analysis | Rattus norvegicus | 18 | ALA3616463 | cell membrane format | Scientific Literature | |
8. | ALA3619814 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 30 uM spermine to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 30 uM spermine | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
9. | ALA3619815 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 10 to 50 mM Tris to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 10 to 50 mM Tris | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
10. | ALA3619816 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of H+ at pH 6.4 to 8.2 to IC50 for NMDA receptor in Wistar rat brain membranes in absence of H+ at pH 6.4 to 8.2 | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
11. | ALA3619817 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 3 to 50 mM Na+ to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 3 to 50 mM Na+ | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
12. | ALA3619818 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 50 mM K+ to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 50 mM K+ | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
13. | ALA3619819 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 20 mM NH4+ to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 20 mM NH4+ | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
14. | ALA3619820 | Binding | Ratio of IC50 for NMDA receptor in Wistar rat brain membranes in presence of 1.3 mM Mg2+ to IC50 for NMDA receptor in Wistar rat brain membranes in absence of 1.3 mM Mg2+ | Rattus norvegicus | 16 | ALA3616463 | cell membrane format | Scientific Literature | |
15. | ALA3745178 | Binding | Negative allosteric modulation of NMDA receptor in rat cerebellar granule cells assessed as suppression of 100 uM glutamate and 30 uM glycine induced-current at 30 uM cotreated with 100 uM NMDA and 50 uM glycine by patch clamp recording method | Rattus norvegicus | 1 | ALA3739344 | assay format | Scientific Literature | |
16. | ALA3745351 | Binding | Negative allosteric modulation of NMDA receptor in rat cerebellar granule cells assessed as suppression of 100 uM glutamate and 30 uM glycine induced-current cotreated with 100 uM NMDA and 50 uM glycine by patch clamp recording method | Rattus norvegicus | 1 | ALA3739344 | assay format | Scientific Literature | |
17. | ALA3745354 | Binding | Binding affinity to rat brain NMDA receptor | Rattus norvegicus | 1 | ALA3739344 | assay format | Scientific Literature | |
18. | ALA3743370 | Binding | Inhibition of rat NMDA receptor PCP binding site at 10 uM | Rattus norvegicus | 1 | ALA3739255 | protein complex format | Scientific Literature | |
19. | ALA3744653 | Binding | Displacement of [3H]CGP39653 from NMDA receptor in Sprague-Dawley rat brain synaptic membrane | Rattus norvegicus | 8 | ALA3739293 | assay format | Scientific Literature | |
20. | ALA3745348 | Binding | Displacement of [3H]CGP39653 from NMDA receptor in rat cortical synaptosomes | Rattus norvegicus | 4 | ALA3739260 | subcellular format | Scientific Literature |