# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA827000 | B | Binding affinity against p53-binding site of Benzodiazepinedione HDM2 | Homo sapiens | 2 | ALA1142679 | protein format | Scientific Literature | |
2. | ALA832457 | B | In vitro inhibitory concentration against p53-mdm2 interaction | 1 | ALA1137206 | protein format | Scientific Literature | ||
3. | ALA828551 | B | Inhibitory activity against MDM2 (murine double minute-2 gene) binding to p53 | Homo sapiens | 1 | ALA1140309 | protein format | Scientific Literature | |
4. | ALA828042 | B | Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells | Homo sapiens | 32 | ALA1142026 | cell-based format | Scientific Literature | |
5. | ALA831913 | B | In vitro inhibitory concentration against p53-mdm2 interaction; Range = 9.6 to 14 uM | 1 | ALA1137206 | protein format | Scientific Literature | ||
6. | ALA833471 | B | Inhibition of p53-binding to HDM2 (human MDM2) by fluorescence polarization peptide displacement assay | Homo sapiens | 44 | ALA1140282 | protein format | Scientific Literature | |
7. | ALA835256 | B | Potency against MDM2 (murine double minute-2 gene) binding to p53; Range =100-300 nM | Homo sapiens | 3 | ALA1140309 | protein format | Scientific Literature | |
8. | ALA831937 | B | In vitro inhibitory concentration against p53-mdm2 interaction at 100 uM | 1 | ALA1137206 | protein format | Scientific Literature | ||
9. | ALA908897 | B | Inhibition of p53-MDM2 interaction by ELISA | Homo sapiens | 93 | ALA1137314 | protein format | Scientific Literature | |
10. | ALA907753 | F | Induction of p53 dependent transcription in SJSA cell line by reporter gene assay | Homo sapiens | 2 | ALA1137314 | cell-based format | Scientific Literature | |
11. | ALA1052159 | B | Inhibition of human MDM2/P53 interaction by HTRF assay | Homo sapiens | 32 | ALA1154659 | protein format | Scientific Literature | |
12. | ALA1052160 | B | Inhibition of human MDM2/P53 interaction by SPR directed binding assay | Homo sapiens | 1 | ALA1154659 | protein format | Scientific Literature | |
13. | ALA1040569 | B | Inhibition of MDM2-p53 interaction in human SJSA1 cells assessed as p53 activation by Western blot | Homo sapiens | 2 | ALA1154717 | cell-based format | Scientific Literature | |
14. | ALA1040570 | B | Inhibition of MDM2-p53 interaction in human SJSA1 cells assessed as increase in MDM2 protein level by Western blot | Homo sapiens | 2 | ALA1154717 | cell-based format | Scientific Literature | |
15. | ALA1040571 | B | Inhibition of MDM2-p53 interaction in human SJSA1 cells assessed as increase in p21 protein level by Western blot | Homo sapiens | 2 | ALA1154717 | cell-based format | Scientific Literature | |
16. | ALA1040572 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells expressing wild type p53 assessed as p53 activation by Western blot | Homo sapiens | 1 | ALA1154717 | cell-based format | Scientific Literature | |
17. | ALA1040573 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells expressing wild type p53 assessed as increase in MDM2 protein level by Western blot | Homo sapiens | 1 | ALA1154717 | cell-based format | Scientific Literature | |
18. | ALA1040574 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells expressing wild type p53 assessed as increase in p21 protein level by Western blot | Homo sapiens | 1 | ALA1154717 | cell-based format | Scientific Literature | |
19. | ALA1040575 | B | Inhibition of MDM2-p53 interaction in human HCT116 cells deficient in wild type p53 by Western blot | Homo sapiens | 1 | ALA1154717 | cell-based format | Scientific Literature | |
20. | ALA1040576 | B | Inhibition of MDM2-p53 interaction in human SJSA1 cells assessed as p53 activation at 0.5 uM by Western blot | Homo sapiens | 1 | ALA1154717 | cell-based format | Scientific Literature |