# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1175217 | B | Inhibition of PIP5K1C at 10 uM | 2 | ALA1177794 | single protein format | Scientific Literature | ||
2. | ALA1908448 | B | Binding constant for PIP5K1C kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
3. | ALA2212496 | B | Inhibition of PIP5K1C assessed as residual activity at 10 uM relative to control | 1 | ALA2203081 | single protein format | Scientific Literature | ||
4. | ALA3111944 | B | Inhibition of PIP5K1C (unknown origin) assessed as residual activity at 10 uM after 1 hr by qPCR analysis relative to control | Homo sapiens | 1 | ALA3108735 | single protein format | Scientific Literature | |
5. | ALA3130921 | B | Inhibition of human PIP5K1gamma assessed as residual activity at 1 uM relative to control | Homo sapiens | 3 | ALA3124838 | single protein format | Scientific Literature | |
6. | ALA3603395 | B | Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay | Homo sapiens | 44 | ALA3600363 | single protein format | Scientific Literature | |
7. | ALA3826092 | B | Inhibition of partial length human wild type PIP5K1C (M1 to T668 residues) expressed in mammalian expression system at 1 uM by KINOMEScan assay relative to control | Homo sapiens | 1 | ALA3822434 | assay format | Scientific Literature | |
8. | ALA3864834 | B | Competitive binding affinity to partial length wild type human PIP5K1C expressed in mammalian expression system at 10 uM by kinomescan method relative to control | Homo sapiens | 1 | ALA3864151 | assay format | Scientific Literature | |
9. | ALA4025325 | B | Inhibition of wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual activity at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4024706 | assay format | Scientific Literature | |
10. | ALA4044136 | B | Inhibition of wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in HEK293 cells assessed as residual activity at 1000 nM after 30 mins by Kinomescan method relative to control | Homo sapiens | 1 | ALA4043093 | cell-based format | Scientific Literature | |
11. | ALA4054982 | B | Inhibition of wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual activity at 50 nM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4052645 | assay format | Scientific Literature | |
12. | ALA4157215 | B | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual binding at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4152344 | assay format | Scientific Literature | |
13. | ALA4181239 | B | Inhibition of recombinant human full length N-terminal His- tagged PIP5K1gamma expressed in baculovirus Sf21 insect cells at 10 uM by filter binding radioactive ATP transferase assay relative to control | Homo sapiens | 1 | ALA4177654 | cell-based format | Scientific Literature | |
14. | ALA4185994 | B | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in HEK293 cells at 1 uM by Kinomescan method relative to control | Homo sapiens | 2 | ALA4184148 | cell-based format | Scientific Literature | |
15. | ALA4191131 | B | Inhibition of recombinant full-length human PIP5K1gamma at 1 uM using phosphatidylinositol 4-phosphate/phosphatidylserine as substrate after 40 mins in presence of [gamma-33P]ATP by scintillation counting method | Homo sapiens | 1 | ALA4190187 | single protein format | Scientific Literature | |
16. | ALA4230894 | B | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4229344 | assay format | Scientific Literature | |
17. | ALA4264483 | B | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as remaining unbound target protein level at 1000 nM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4261600 | assay format | Scientific Literature | |
18. | ALA4266613 | B | Inhibition of recombinant human full length N-terminal His6-tagged PIP5K1gamma expressed in baculovirus infected Sf21 insect cells at 1 uM relative to control | Homo sapiens | 3 | ALA4265877 | cell-based format | Scientific Literature | |
19. | ALA4307992 | B | Binding affinity to wild-type human partial length PIP5K1C (M1 to T668 residues) expressed in mammalian expression system assessed as residual binding level at 10 uM by Kinomescan method relative to control | Homo sapiens | 1 | ALA4304811 | assay format | Scientific Literature | |
20. | ALA4314956 | B | Inhibition of recombinant full-length human PIP5K1gamma assessed as residual activity at 10 uM using phosphatidylinositol 4-phosphate as substrate measured after 40 mins by HTRF assay | Homo sapiens | 1 | ALA4311992 | single protein format | Scientific Literature |