# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3626284 | Binding | Inhibition of MAP3K2 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3621137 | single protein format | Scientific Literature | |
2. | ALA3631014 | Binding | Inhibition of Dox inducible human DLK transfected in HEK293 cells assessed as reduction in JNK phosphorylation incubated for 5.5 hrs measured by Hoechst 33342 staining based imaging analysis | Homo sapiens | 7 | ALA3627690 | cell-based format | Scientific Literature | |
3. | ALA3631015 | Binding | Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 14 | ALA3627690 | single protein format | Scientific Literature | |
4. | ALA3631022 | Binding | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of MKK4 at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | ALA3627690 | cell-based format | Scientific Literature | |
5. | ALA3631023 | Binding | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of MKK7 at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | ALA3627690 | cell-based format | Scientific Literature | |
6. | ALA3631024 | Binding | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of JNK at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | ALA3627690 | cell-based format | Scientific Literature | |
7. | ALA3631025 | Binding | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of c-Jun at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | ALA3627690 | cell-based format | Scientific Literature | |
8. | ALA3721107 | Binding | Inhibition of N-terminally GST-tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminal His-tagged MKK4 K131M substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 182 | ALA3714745 | single protein format | Patent Bioactivity Data | |
9. | ALA3734233 | Binding | Inhibition of N-terminally GST-tagged human DLK catalytic domain (1 to 520 amino acids) using N- terminal His-tagged MKK4 K131M substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 427 | ALA3727347 | single protein format | Patent Bioactivity Data | |
10. | ALA3749005 | Binding | Inhibition of human DLK using MBP as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
11. | ALA4352341 | Binding | Inhibition of human DLK at 10 uM using MBP as substrate in presence of [gamma-33P]-ATP | Homo sapiens | 1 | ALA4350963 | single protein format | Scientific Literature | |
12. | ALA1908459 | Binding | Binding constant for DLK kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
13. | ALA3395585 | Binding | Inhibition of DLK (unknown origin) | Homo sapiens | 33 | ALA3393025 | single protein format | Scientific Literature | |
14. | ALA3395586 | Binding | Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay | Homo sapiens | 25 | ALA3393025 | cell-based format | Scientific Literature | |
15. | ALA2014917 | Binding | Inhibition of DLK at 10 uM | 1 | ALA2010722 | single protein format | Scientific Literature | ||
16. | ALA4119867 | Binding | Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4 K131M as substrate after 60 mins in presence of ATP by TR-FRET assay | Homo sapiens | 28 | ALA4118097 | cell-based format | Scientific Literature | |
17. | ALA4119868 | Binding | Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay | Homo sapiens | 26 | ALA4118097 | cell-based format | Scientific Literature | |
18. | ALA4119875 | Binding | Binding affinity to full length wild type human DLK (M1 to P859 residues) expressed in mammalian cells by KINOMEscan assay | Homo sapiens | 2 | ALA4118097 | cell-based format | Scientific Literature | |
19. | ALA4120233 | Binding | Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs in presence of 10% bovine serum by Hoechst-33342 staining-based assay | Homo sapiens | 1 | ALA4118097 | cell-based format | Scientific Literature | |
20. | ALA4326804 | Binding | Inhibition of DLK (unknown origin) | Homo sapiens | 1 | ALA4325851 | single protein format | Scientific Literature |