| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1908459 | B | Binding constant for DLK kinase domain | 72 | single protein format | Scientific Literature | |||
| 2. | ALA2014917 | B | Inhibition of DLK at 10 uM | 1 | single protein format | Scientific Literature | |||
| 3. | ALA3395585 | B | Inhibition of DLK (unknown origin) | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 4. | ALA3395586 | B | Inhibition of human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 5. | ALA3626284 | B | Inhibition of MAP3K2 (unknown origin) at 1 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3631014 | B | Inhibition of Dox inducible human DLK transfected in HEK293 cells assessed as reduction in JNK phosphorylation incubated for 5.5 hrs measured by Hoechst 33342 staining based imaging analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA3631015 | B | Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 8. | ALA3631022 | B | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of MKK4 at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3631023 | B | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of MKK7 at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3631024 | B | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of JNK at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3631025 | B | Inhibition of Flag DLK (unknown origin) transfected in HEK293 cells assessed as reduction of phosphorylation of c-Jun at 0.1 to 10 uM incubated for 5 hrs measured by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3721107 | B | Inhibition of N-terminally GST-tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminal His-tagged MKK4 K131M substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 182 | single protein format | Patent Bioactivity Data | ||
| 13. | ALA3734233 | B | Inhibition of N-terminally GST-tagged human DLK catalytic domain (1 to 520 amino acids) using N- terminal His-tagged MKK4 K131M substrate incubated for 60 mins by TR-FRET assay | Homo sapiens | 427 | single protein format | Patent Bioactivity Data | ||
| 14. | ALA3749005 | B | Inhibition of human DLK using MBP as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4119867 | B | Binding affinity to N-terminally GST-tagged wild type human DLK (1 to 520 residues) expressed in sf21 insect cells using N-terminally His-tagged MKK4 K131M as substrate after 60 mins in presence of ATP by TR-FRET assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 16. | ALA4119868 | B | Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs by Hoechst-33342 staining-based assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 17. | ALA4119875 | B | Binding affinity to full length wild type human DLK (M1 to P859 residues) expressed in mammalian cells by KINOMEscan assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4120233 | B | Inhibition of doxycycline inducible human DLK transfected in HEK293 cells assessed as JNK phosphorylation after 5.5 hrs in presence of 10% bovine serum by Hoechst-33342 staining-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4326804 | B | Inhibition of DLK (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4327663 | B | Inhibition of human DLK assessed as residual activity at 1 uM using MBP as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature |
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