| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1913981 | B | Irreversible inhibition of PAD2 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay in presence of 2 mM benzoyl-L-arginine ethyl ester | 2 | single protein format | Scientific Literature | |||
| 2. | ALA1913985 | B | Irreversible inhibition of PAD2 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay in presence of 10 mM benzoyl-L-arginine ethyl ester | 2 | single protein format | Scientific Literature | |||
| 3. | ALA1914036 | B | Ratio of Kinact to Ki for F-amidine to compound for PAD2 | 1 | single protein format | Scientific Literature | |||
| 4. | ALA1914040 | B | Ratio of Kinact to Ki for Cl-amidine to compound for PAD2 | 1 | single protein format | Scientific Literature | |||
| 5. | ALA1914013 | B | Irreversible inhibition of PAD2 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluorometric analysis | 4 | single protein format | Scientific Literature | |||
| 6. | ALA1914102 | B | Irreversible inhibition of PAD2 assessed as residual activity at 1 mM measured after 20 hrs by colorimetric assay | 4 | single protein format | Scientific Literature | |||
| 7. | ALA1914106 | B | Irreversible inhibition of PAD2 assessed as residual activity measured after 20 hrs by colorimetric assay | 3 | single protein format | Scientific Literature | |||
| 8. | ALA1914110 | B | Ratio of Kinact to Ki for PAD2 | 4 | single protein format | Scientific Literature | |||
| 9. | ALA2212943 | B | Ratio of Kinact to Ki for PAD2 | 11 | single protein format | Scientific Literature | |||
| 10. | ALA3117728 | B | Binding affinity to PAD2 C647A mutant (unknown origin) assessed as mass shift of enzyme at 1:10 enzyme to compound ratio preincubated for 1 hr followed by overnight dialysis in double distilled water by MALDI mass spectrometric analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA3117729 | B | Binding affinity to recombinant wild-type PAD2 (unknown origin) assessed as mass shift of enzyme at 1:10 enzyme to compound ratio preincubated for 1 hr followed by overnight dialysis in double distilled water by MALDI mass spectrometric analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA3117922 | B | Competitive inhibition of recombinant wild-type PAD2 (unknown origin) at 0.1 to 2.5 uM by fluorescence polarization-ABPP assay in presence of RFA | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3117925 | B | Ratio of Kinact to Ki(app) for recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 10 mins followed by substrate addition measured after 15 mins by COLDER assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 14. | ALA3119085 | B | Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 10 mins followed by substrate addition measured after 15 mins by COLDER assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3119089 | B | Irreversible inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate assessed as residual activity at 170-fold excess of compound after 1 hr by dialysis method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3119094 | B | Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 17. | ALA3119098 | B | Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate assessed as residual activity at 10 uM preincubated for 15 mins followed by substrate addition measured after 15 mins by COLDER assay relative to control | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 18. | ALA3414099 | B | Inhibition of PAD2 (unknown origin) using N-alpha-benzoyl-L-arginine ethyl ester as substrate assessed as citrulline production after 15 mins by COLDER assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3414100 | B | Ratio of Kinact to Ki for PAD2 (unknown origin) using N-alpha-benzoyl-L-arginine ethyl ester as substrate assessed as citrulline production after 15 mins by COLDER assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA3870224 | B | Inhibition of N-terminal 6His/FLAG-tagged recombinant human PAD2 (1 to 665 residues) expressed in baculovirus infected sf9 cells using N-a-benzoyl-L-arginine ethyl ester as substrate preincubated for 30 mins followed by substrate addition after 90 mins by DTT-based fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature |
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