# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3429862 | Binding | Inhibition of human Src | Homo sapiens | 27 | ALA3425429 | single protein format | Scientific Literature | |
2. | ALA3429868 | Binding | Inhibition of human Src T341M mutant | Homo sapiens | 1 | ALA3425429 | single protein format | Scientific Literature | |
3. | ALA3428742 | Binding | Inhibition of Src (unknown origin) assessed as remaining activity at 100 uM by radioactive filter binding assay in presence of [33P]-ATP relative to control | Homo sapiens | 16 | ALA3425453 | single protein format | Scientific Literature | |
4. | ALA3430222 | Binding | Induction of covalent modification of c-Src kinase domain (251 to 533 residues) T338M/S345C mutant (unknown origin) at 100 uM incubated for 1 hr by mass spectrometry method | Homo sapiens | 2 | ALA3425413 | single protein format | Scientific Literature | |
5. | ALA3430223 | Binding | Induction of covalent modification of wild type c-Src kinase domain (251 to 533 residues) (unknown origin) at 100 uM incubated for 1 hr by mass spectrometry method | Homo sapiens | 2 | ALA3425413 | single protein format | Scientific Literature | |
6. | ALA3430224 | Binding | Induction of covalent modification of c-Src kinase domain (251 to 533 residues) T338M/S345C mutant (unknown origin) assessed as protein mass increase at 100 uM incubated for 1 hr by mass spectrometry method | Homo sapiens | 2 | ALA3425413 | single protein format | Scientific Literature | |
7. | ALA3427997 | Binding | Binding affinity to c-Src in human MCF7 cells by SDS-PAGE based pull-down assay | Homo sapiens | 3 | ALA3425432 | cell-based format | Scientific Literature | |
8. | ALA3428253 | Binding | Inhibition of Src phosphorylation in human MDA-MB-231 cells after 20 hrs by Western blot analysis | Homo sapiens | 1 | ALA3425429 | cell-based format | Scientific Literature | |
9. | ALA3428254 | Binding | Inhibition of Src in human MDA-MB-231 cells assessed as reduction of FAK phosphorylation at >0.03 uM after 20 hrs by Western blot analysis | Homo sapiens | 2 | ALA3425429 | cell-based format | Scientific Literature | |
10. | ALA3428258 | Binding | Inhibition of Src phosphorylation in human MDA-MB-231 cells at 0.001 to 1 uM after 20 hrs by Western blot analysis | Homo sapiens | 1 | ALA3425429 | cell-based format | Scientific Literature | |
11. | ALA3428989 | Binding | Inhibition of human c-Src using poly[Glu:Tyr] (4:1) peptide substrate at 1 uM by 33P Hotspot assay | Homo sapiens | 1 | ALA3425491 | single protein format | Scientific Literature | |
12. | ALA3429152 | Binding | Inhibition of human c-Src using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assay | Homo sapiens | 1 | ALA3425491 | single protein format | Scientific Literature | |
13. | ALA3578905 | Binding | Competitive binding affinity to SRC in human A375 cells after 15 mins in presence of ATP analogue | Homo sapiens | 1 | ALA3576847 | cell-based format | Scientific Literature | |
14. | ALA3580030 | Binding | Inhibition of human cSRC assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | ALA3576773 | single protein format | Scientific Literature | |
15. | ALA3580046 | Binding | Inhibition of human Src (1-530) assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | ALA3576773 | single protein format | Scientific Literature | |
16. | ALA3580047 | Binding | Inhibition of human Src T341M mutant assessed as residual activity at 10 uM relative to control | Homo sapiens | 1 | ALA3576773 | single protein format | Scientific Literature | |
17. | ALA3583142 | Binding | Inhibition of Tel-fused SRC (unknown origin) expressed in mouse BA/F3 cells after 48 hrs by luciferase reporter gene assay in absence of recombinant mouse IL3 | Homo sapiens | 3 | ALA3580662 | cell-based format | Scientific Literature | |
18. | ALA3585224 | Binding | Inhibition of human his-tagged full length Src active enzyme using KVEKIGEGTYGVVYK substrate by scintillation counting analysis | Homo sapiens | 10 | ALA3580596 | single protein format | Scientific Literature | |
19. | ALA3585225 | Binding | Inhibition of human his-tagged full length Src active enzyme using KVEKIGEGTYGVVYK substrate at 100 uM by scintillation counting analysis | Homo sapiens | 4 | ALA3580596 | single protein format | Scientific Literature | |
20. | ALA3587040 | Binding | Inhibition of SRC (unknown origin) using ATP and polyE4Y substrate by radiometric assay | Homo sapiens | 2 | ALA3585282 | single protein format | Scientific Literature |