# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1942533 | B | Inhibition of LSD2 | 1 | ALA1938384 | single protein format | Scientific Literature | ||
2. | ALA2447183 | B | Inhibition of recombinant LSD2 (22 to 822 aa) (unknown origin) expressed in Escherichia coli BL21(DE) by fluorescence assay | Homo sapiens | 3 | ALA2440118 | assay format | Scientific Literature | |
3. | ALA3766872 | B | Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic analysis | Homo sapiens | 6 | ALA3763075 | single protein format | Scientific Literature | |
4. | ALA3776537 | B | Inhibition of LSD2 in human HeLa cells assessed as H3K4me1/H3 ratio at 20 uM after 24 hrs by Western blot analysis in absence of fetal bovine serum (Rvb = 1 No_unit) | Homo sapiens | 2 | ALA3774333 | cell-based format | Scientific Literature | |
5. | ALA3776539 | B | Inhibition of full length N-terminal His-tagged human LSD2 (1 to 822 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me2 peptide substrate by MALDI-TOF mass spectrometric analysis | Homo sapiens | 8 | ALA3774333 | cell-based format | Scientific Literature | |
6. | ALA3777879 | B | Inhibition of LSD2 in human HeLa cells assessed as H3K4me1/H3 ratio at 5 uM after 24 hrs by Western blot analysis in absence of fetal bovine serum (Rvb = 1 No_unit) | Homo sapiens | 2 | ALA3774333 | cell-based format | Scientific Literature | |
7. | ALA3777880 | B | Inhibition of LSD2 in human HeLa cells assessed as H3K4me1/H3 ratio at 10 uM after 24 hrs by Western blot analysis in absence of fetal bovine serum (Rvb = 1 No_unit) | Homo sapiens | 2 | ALA3774333 | cell-based format | Scientific Literature | |
8. | ALA3782875 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 14 | ALA3779820 | single protein format | Scientific Literature | |
9. | ALA4008772 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 6 | ALA4007415 | single protein format | Scientific Literature | |
10. | ALA4008796 | B | Inhibition of KDM1B (unknown origin) | Homo sapiens | 4 | ALA4007416 | single protein format | Scientific Literature | |
11. | ALA4135163 | B | Inhibition of human full length LSD2 using biotin-labeled H3K4me2 (1 to 24 residues) as substrate after 1 hr by TR-FRET assay | Homo sapiens | 18 | ALA4130492 | single protein format | Scientific Literature | |
12. | ALA4703541 | B | Inhibition of LSD2 (unknown origin) at | Homo sapiens | 1 | ALA4699559 | single protein format | Scientific Literature | |
13. | ALA4814429 | B | Inhibition of LSD2 (unknown origin) using Lys4-dimethylated H3 (1-20) peptide as substrate incubated for 30 mins by peroxidase-coupled assay | Homo sapiens | 3 | ALA4813911 | single protein format | Scientific Literature | |
14. | ALA4814443 | B | Inhibition of human LSD2 using Bio-H3K4me2 (1 to 24 residues) as substrate incubated for 1 hr by TR-FRET assay | Homo sapiens | 2 | ALA4813911 | single protein format | Scientific Literature | |
15. | ALA5127917 | B | Binding affinity to KDM1B (unknown origin) assessed as inhibition constant using Lys4-dimethylated H3 peptide as substrate incubated for 30 mins by enzymatic assay | Homo sapiens | 1 | ALA5126529 | single protein format | Scientific Literature | |
16. | ALA5136948 | B | Inhibition of LSD2 (unknown origin) (26 to 822 residues) expressed in baculovirus-infected Sf9 insect cells using K4-dimethylated H3 as substrate by peroxidase-coupled method | Homo sapiens | 43 | ALA5131575 | cell-based format | Scientific Literature | |
17. | ALA5136955 | B | Inhibition of human LSD2 in human CCRF-CEM cells assessed as fold increase in H3K4me2 level at 20 uM after 24 hrs by western blot analysis | Homo sapiens | 2 | ALA5131575 | cell-based format | Scientific Literature | |
18. | ALA5159713 | B | Inhibition of recombinant human full length LSD2 using biotinylated H3K4Me2 peptide as substrate by TR-FRET assay | Homo sapiens | 24 | ALA5154758 | single protein format | Scientific Literature | |
19. | ALA5159741 | B | Inhibition of human LSD2 using H3K4Me2 peptide as substrate incubated for 60 min by peroxidase-coupled method | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature | |
20. | ALA5159744 | B | Inhibition of human LSD2 | Homo sapiens | 1 | ALA5154758 | single protein format | Scientific Literature |