| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1941901 | B | Inhibition of N-terminal histidine-tagged PPM1Dc after 10 mins using BIOMOL GREEN assay | 1 | ALA1938369 | single protein format | Scientific Literature | ||
| 2. | ALA1941223 | B | Inhibition of N-terminal histidine-tagged PPM1Dc at 4 uM after 10 mins by BIOMOL GREEN assay | 5 | ALA1938369 | single protein format | Scientific Literature | ||
| 3. | ALA1941224 | B | Inhibition of PPM1D in human MCF7 cells assessed as increase in p53 phosphorylation at Ser15 by Western blot analysis | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
| 4. | ALA1941225 | B | Inhibition of PPM1D in UV-irradiated human MCF7 cells assessed as increase in p53 phosphorylation at Ser15 measuring p53 protein level by Western blot analysis | Homo sapiens | 1 | ALA1938369 | cell-based format | Scientific Literature | |
| 5. | ALA3111818 | B | Inhibition of N-terminal His-tagged human PPM1D (1 to 420) assessed as phosphoric acid release after 30 mins | Homo sapiens | 1 | ALA3108742 | single protein format | Scientific Literature | |
| 6. | ALA3376100 | B | Inhibition of C-terminal truncated PPM1D in human HCT116 cells assessed as increase in Ser15 phosphorylated p53 level at 2 uM after 24 to 48 hrs by western blotting | Homo sapiens | 1 | ALA3351350 | cell-based format | Scientific Literature | |
| 7. | ALA3376101 | B | Inhibition of C-terminal truncated PPM1D in human HCT116 cells assessed as increase in Ser15 phosphorylated p53 level at 40 uM after 24 to 48 hrs by western blotting in presence of doxorubicin | Homo sapiens | 1 | ALA3351350 | cell-based format | Scientific Literature | |
| 8. | ALA3376102 | B | Inhibition of C-terminal truncated PPM1D in human HCT116 cells assessed as increase in p21 level at 2 uM after 24 to 48 hrs by western blotting | Homo sapiens | 1 | ALA3351350 | cell-based format | Scientific Literature | |
| 9. | ALA3376103 | B | Inhibition of C-terminal truncated PPM1D in human HCT116 cells assessed as increase in p21 level at 40 uM after 24 to 48 hrs by western blotting in presence of doxorubicin | Homo sapiens | 1 | ALA3351350 | cell-based format | Scientific Literature | |
| 10. | ALA3362813 | B | Inhibition of PPM1D (unknown origin) phosphatase activity using peptide substrate TDDEMT*GY*VAT by malachite green/molybdate based assay | Homo sapiens | 26 | ALA3352140 | single protein format | Scientific Literature | |
| 11. | ALA3362825 | B | Inhibition of PPM1D in human SMOV2 cells assessed as increase in P-S15-p53 level at 1.25 to 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3352140 | cell-based format | Scientific Literature | |
| 12. | ALA3363063 | B | Inhibition of PPM1D in non-amplified human TOV21G cells assessed as increase in P-S15-p53 level at 1.25 to 5 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3352140 | cell-based format | Scientific Literature | |
| 13. | ALA3614136 | B | Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-NH2 substrate | Homo sapiens | 4 | ALA3612007 | cell-based format | Scientific Literature | |
| 14. | ALA3614138 | B | Non-competitive inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-NH2 substrate by Lineweaver-Burk plot | Homo sapiens | 1 | ALA3612007 | cell-based format | Scientific Literature | |
| 15. | ALA3614144 | B | Inhibition of PPM1D in UV irradiated human MCF7 cells assessed as increase in p53 Ser15 phosphorylation by Western blotting method | Homo sapiens | 1 | ALA3612007 | cell-based format | Scientific Literature | |
| 16. | ALA3614145 | B | Inhibition of PPM1D in UV irradiated human MCF7 cells assessed as increase in p53 protein expression by Western blotting method | Homo sapiens | 1 | ALA3612007 | cell-based format | Scientific Literature | |
| 17. | ALA4425342 | B | Inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus-infected insect SF9 cells assessed as fluorescein diphosphate hydrolysis after 5 mins by fluorescence assay | Homo sapiens | 1 | ALA4425089 | cell-based format | Scientific Literature | |
| 18. | ALA4668459 | B | Allosteric inhibition of human Wip1 (2 to 420 residues) expressed in baculovirus infected sf9 cells using FDP as substrate by fluorescence method | Homo sapiens | 1 | ALA4665677 | cell-based format | Scientific Literature |
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