| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA822092 | B | Proteolysis rate constant (Kcat), when mixed with trypsin enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 2. | ALA822093 | B | Inhibition constant (Ki) against trypsin enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 3. | ALA822094 | B | Inhibition constant (Ki) against trypsin enzyme. | Sus scrofa | 3 | single protein format | Scientific Literature | ||
| 4. | ALA822095 | B | Inhibition constant (Ki) when mixed with p-nitroanilide against trypsin enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 5. | ALA857015 | B | Proteolysis constant (Km), when mixed with trypsin enzyme for the conversion of water-soluble compound to fluorescent oil-soluble compound | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 6. | ALA816147 | B | Inhibitory activity against porcine pancreatic trypsin (TRP) | Sus scrofa | 30 | single protein format | Scientific Literature | ||
| 7. | ALA826338 | B | Binding affinity value against trypsin | Sus scrofa | 19 | single protein format | Scientific Literature | ||
| 8. | ALA828785 | B | Binding affinity value against trypsin; NT means not tested | Sus scrofa | 8 | single protein format | Scientific Literature | ||
| 9. | ALA995689 | B | Inhibition of pig pancreatic trypsin after 15 mins | Sus scrofa | 14 | single protein format | Scientific Literature | ||
| 10. | ALA1107883 | B | Inhibition of pig pancreas trypsin at 10 uM preincubated for 10 mins by spectrophotometry | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 11. | ALA1738079 | B | PUBCHEM_BIOASSAY: Trypsin Inhibition Assay Measured in Biochemical System Using Plate Reader - 2034-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2618] | Sus scrofa | 232 | biochemical format | PubChem BioAssays | ||
| 12. | ALA2320210 | B | Inhibition of pig trypsin using CH3SO2-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysis | Sus scrofa | 14 | single protein format | Scientific Literature | ||
| 13. | ALA3091124 | A | Stability of the compound assessed as porcine pancreatic trypsin-mediated compound degradation at 0.1 mM after 5 hrs by reverse-phase HPLC/MS analysis | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 14. | ALA3091127 | A | Stability of the compound assessed as porcine pancreatic trypsin-mediated compound degradation at 0.1 mM after 10 secs by reverse-phase HPLC/MS analysis | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3091128 | A | Stability of the compound assessed as porcine pancreatic trypsin-mediated compound degradation at 0.1 mM after 8 hrs by reverse-phase HPLC/MS analysis | Sus scrofa | 2 | single protein format | Scientific Literature | ||
| 16. | ALA3091130 | A | Stability of the compound assessed as half life of porcine pancreatic trypsin-mediated compound degradation at 0.1 mM by reverse-phase HPLC/MS analysis | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3363612 | B | Inhibition of pig pancreas trypsin type IX-S using Boc-Gln-Ala-Arg-MCA substrate by 7-amino-4-methylcoumarin release based spectrofluorometry | Sus scrofa | 4 | single protein format | Scientific Literature | ||
| 18. | ALA3363613 | B | Inhibition of pig pancreas trypsin type IX-S | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3363614 | B | Reversible slow binding inhibition of pig pancreas trypsin type IX-S using Boc-Gln-Ala-Arg-MCA substrate by 7-amino-4-methylcoumarin release based spectrofluorometry | Sus scrofa | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3887551 | B | High-Throughput Screening Assay: To identify novel inhibitors of hepsin, the Chembridge DIVERSet 10,000 compound high-diversity library was screened using an assay based on the cleavage of the chromogenic peptide. In addition, the NINDS II library of 1040 compounds (MicroSource Discovery) was screened to identify hepsin inhibitors among established drugs and known bioactive molecules. Screens were performed in a 96-well format at a final compound concentration of 2 uM. To minimize false positives, positions 1 and 12 of each row contained DMSO/buffer controls. As a measure of reproducibility, the Z' score for this assay was 0.78 (Zhang et al., 1999 J Biomol Screen 4:67). | Sus scrofa | 16 | single protein format | BindingDB Database |
The page will load shortly, Thanks for your patience!